1. Volume 128, Issue 7, Pages 1819-1829 (June 2005)
Brain Response to Visceral Aversive Conditioning: A Functional Magnetic Resonance Imaging Study 
Lidia Yágüez, Steven Coen, Lloyd J. Gregory, Edson Amaro, Christian Altman, Michael J. Brammer, Edward T. Bullmore, Steven C.R. Williams, Qasim Aziz 
Gastroenterology 
Volume 128, Issue 7, Pages (June 2005)
DOI: /j.gastro
Copyright © 2005 American Gastroenterological Association Terms and Conditions

2. Figure 1
Generic brain activation during the esophageal distention condition. (A) Generic brain activation during the learning phase, ie, painful esophageal distention. (B) Anticipation phase and (C) extinction phase. Left, axial view (A: x = 40; y = 10; z = −2; B: x = 40; y = 10; z = −2; C: x = 40; y = 10; z = −2); middle row, right sagittal view (A: x = 32; y = 17; z = −13; B: x = 36; y = 13; z = −13; C: x = 32; y = 13; z = −13); right column, axial view (A: x = 43; y = 13; z = 30; B: x = 43; y = 13; z = 30; C: x = 43; y = 13; z = 28). Note the activation of the insula, right inferior frontal gyrus, and anterior cingulate cortex (ACC) in (A), (B), and (C). Activation in the dorsolateral prefrontal cortex (DLPFC) was found only in the (B) anticipation and (C) extinction phases. The generic brain activations are superimposed on a structural template.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

3. Figure 2
Generic brain activation during the air puff stimulation condition. (A) Generic brain activation during the learning phase with the mid anterior cingulate cortex (ACC) in axial view (x = 4; y = 4; z = 42) in the left row, the right primary somatosensory area (SI) in sagittal view (x = 53; y = −26; z = 15) in the middle row, and the left insula activity in axial view in the right column (x = −32; y = 13; z = −2). (B) Anticipation phase. Left is the angular gyrus activation displayed in an axial view (x = −47; y = −60; z = 37), and in the middle is the supramarginal gyrus in a coronal view (x = 40; y = 56; z = 37). The generic brain activations are superimposed on a structural template.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

4. Figure 3
Trend analysis of mean sums of squares ratio (SSQ). Esophageal condition. ACC, mid anterior cingulate gyrus, Brodmann area 24; SMA, supplementary motor area; L, left; R, right; SII, secondary somatosensory cortex. Notice the significant decrease in activity across the 3 experimental phases for ACC and SMA. The changes in SSQ for the other brain areas did not yield a significant trend.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

5. Figure 4
Generic brain activation during the painful esophageal distention condition. Generic brain activation with the SMA in axial view during the learning phase (x = 4; y = −4; z = 48), anticipation phase (x = 4; y = −4; z = 48), and extinction phase (x = 4; y = −4; z = 48).
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions