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Mite allergen exposure is a risk for the incidence of specific sensitization  Joachim Kuehr, MDa, Thomas Frischer, MDa, Rolf Meinert, MSca, Regina Barth,

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Presentation on theme: "Mite allergen exposure is a risk for the incidence of specific sensitization  Joachim Kuehr, MDa, Thomas Frischer, MDa, Rolf Meinert, MSca, Regina Barth,"— Presentation transcript:

1 Mite allergen exposure is a risk for the incidence of specific sensitization 
Joachim Kuehr, MDa, Thomas Frischer, MDa, Rolf Meinert, MSca, Regina Barth, MDa, Johannes Forster, MDa, Sabine Schrauba, Radvan Urbanek, MDb, Wilfried Karmaus, MD, MPHc  Journal of Allergy and Clinical Immunology  Volume 94, Issue 1, Pages (July 1994) DOI: / (94) Copyright © 1994 Mosby, Inc. Terms and Conditions

2 FIG. 1 Numbers of transitions regarding status of sensitization to Dpt from first to second SPT (period I) and from second to third SPT (period II), respectively. Numbers in parentheses are numbers of participants with a respective Der p I exposure measurement. [0], No sensitization (no wheal); [1], doubtful sensitization; [2], definite sensitization. Journal of Allergy and Clinical Immunology  , 44-52DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

3 FIG. 2 LogORs for relationship between Der p I exposure and risk for a definite incidence of sensitization to Dpt in the total population. LogORs (solid line) and 95% CIs (dashed lines) are based on logistic regressions with a spectrum of 30 dichotomous cutoff points for the Der p I concentration. Analyses are controlled for initial at least doubtful sensitization to Df, initial definite sensitization to one of five non-mite allergens, gender, parental atopy, and low gestational age. Journal of Allergy and Clinical Immunology  , 44-52DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

4 FIG. 3 LogORs for relationship between Der p I exposure and risk for a definite incidence of sensitization to Dpt for the subpopulation with an initial non-Dpt sensitization (i.e., at least doubtful sensitization to Df or definite sensitization to one of five non-mite allergens). LogORs (solid line) and 95% CIs (dashed lines) are based on logistic regressions with a spectrum of 30 dichotomous cutoff points for the Der p I concentration. Analyses are controlled for gender, parental atopy, and low gestational age. Journal of Allergy and Clinical Immunology  , 44-52DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions

5 FIG. 4 LogORs for relationship between Der p I exposure and risk for a definite incidence of sensitization to Dpt for the subpopulation without an initial non-Dpt sensitization (i.e., at least doubtful sensitization to Df or definite sensitization to one of five non-mite allergens). LogORs (solid line) and 95% CIs (dashed lines) are based on logistic regressions with a spectrum of 30 dichotomous cutoff points for the Der p I concentration. Analyses are controlled for gender, parental atopy, and low gestational age. Journal of Allergy and Clinical Immunology  , 44-52DOI: ( / (94) ) Copyright © 1994 Mosby, Inc. Terms and Conditions


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