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Volume 147, Issue 2, Pages (August 2014)

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Presentation on theme: "Volume 147, Issue 2, Pages (August 2014)"— Presentation transcript:

1 Volume 147, Issue 2, Pages 502-526 (August 2014)
Guidelines on Genetic Evaluation and Management of Lynch Syndrome: A Consensus Statement by the US Multi-Society Task Force on Colorectal Cancer  Francis M. Giardiello, John I. Allen, Jennifer E. Axilbund, C. Richard Boland, Carol A. Burke, Randall W. Burt, James M. Church, Jason A. Dominitz, David A. Johnson, Tonya Kaltenbach, Theodore R. Levin, David A. Lieberman, Douglas J. Robertson, Sapna Syngal, Douglas K. Rex  Gastroenterology  Volume 147, Issue 2, Pages (August 2014) DOI: /j.gastro Copyright © 2014 American Gastroenterological Association, American College of Gastroenterology, the American Society of Colon and Rectal Surgeons, and the American Society for Gastrointestinal Endoscopy Terms and Conditions

2 Figure 1 Colorectal cancer risk assessment tool.
Adapted with permission from Kastrinos et al.101 Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2014 American Gastroenterological Association, American College of Gastroenterology, the American Society of Colon and Rectal Surgeons, and the American Society for Gastrointestinal Endoscopy Terms and Conditions

3 Figure 2 Universal screening by tumor testing.
Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2014 American Gastroenterological Association, American College of Gastroenterology, the American Society of Colon and Rectal Surgeons, and the American Society for Gastrointestinal Endoscopy Terms and Conditions

4 Figure 3 Traditional testing strategy indications and genetic counseling. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2014 American Gastroenterological Association, American College of Gastroenterology, the American Society of Colon and Rectal Surgeons, and the American Society for Gastrointestinal Endoscopy Terms and Conditions

5 Figure 4 Traditional testing strategy when family mutation known.
Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2014 American Gastroenterological Association, American College of Gastroenterology, the American Society of Colon and Rectal Surgeons, and the American Society for Gastrointestinal Endoscopy Terms and Conditions

6 Figure 5 Traditional testing strategy when patient is clinically affected and the family mutation is unknown. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2014 American Gastroenterological Association, American College of Gastroenterology, the American Society of Colon and Rectal Surgeons, and the American Society for Gastrointestinal Endoscopy Terms and Conditions

7 Figure 6 Traditional testing strategy of at-risk family member when family mutation is unknown. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2014 American Gastroenterological Association, American College of Gastroenterology, the American Society of Colon and Rectal Surgeons, and the American Society for Gastrointestinal Endoscopy Terms and Conditions


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