1. Volume 115, Issue 5, Pages 1113-1122 (November 1998)
Lack of correlation between Lewis antigen expression by Helicobacter pylori and gastric epithelial cells in infected patients 
Diane E. Taylor, David A. Rasko, Richard Sherburne, Clinton Ho, Laurence D. Jewell 
Gastroenterology 
Volume 115, Issue 5, Pages (November 1998)
DOI: /S (98)
Copyright © 1998 American Gastroenterological Association Terms and Conditions

2. Fig. 1
Structures of type 1 and type 2 Le carbohydrate structures. The enzymes required for generation of these structures are as shown next to the arrows and are α1→4-fucosyltransferase (Lea and Leb), α1→3-fucosyltransferase (Lex and Ley), and α1→2-fucosyltransferase (Leb and Ley).
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

3. Fig. 2
(A) Negative control (H. pylori–negative) in which the primary antibody in the reaction was replaced by mouse serum. Neither the superficial mucous cells nor the deep glands showed reactivity (original magnification 110×). (B) Anti-Leb staining of gastric epithelium with H. pylori–associated gastritis. The brown pigmentation indicates positive staining in the superficial mucous cells, deep glands, and luminal secretions. In the stroma, mixed inflammatory cells are evident (original magnification 110×). (C) Anti-Lea staining of gastric epithelium with H. pylori–associated gastritis. The brown pigmentation indicates positive staining in the superficial mucous cells and luminal secretions. In the stroma, mixed inflammatory cells are evident (original magnification 275×). (D) Anti-Lea staining of gastric epithelium with H. pylori–associated gastritis. The brown pigmentation indicates positive staining in the superficial mucous cells, deep glands, and luminal secretions. In the stroma, mixed inflammatory cells are evident (original magnification 440×). (E) Anti-Lex staining of gastric epithelium with H. pylori–associated gastritis. The brown pigmentation indicates positive staining in the superficial mucous cells, deep glands, and luminal secretions. In the stroma, mixed inflammatory cells are evident (original magnification 110×). (F) Anti-Ley staining of gastric epithelium with H. pylori–associated gastritis. The brown pigmentation indicates positive staining in the superficial mucous cells, deep glands, and luminal secretions. In the stroma, mixed inflammatory cells are evident (original magnification 110×).
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

4. Fig. 3
Comparison of degree of expression of Lex and Ley by 24 H. pylori strains determined by ELISA. The black bars represent cagA+ strains and the white bars cagA− strains.
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

5. Fig. 4
Expression of Lex vs. Ley by 24 H. pylori strains. Squares represent cagA− strains, whereas the rest are cagA+ strains.
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

6. Fig. 5
Immunoelectron microscopy of gastric biopsy S showing reactivity with Lex (20-nm gold particles) and with Ley (10-nm gold particles) expressed by gastric epithelial cells (bar = 1 μm).
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

7. Fig. 6
Immunoelectron microscopy of whole cells of H. pylori UA1182 cultured from biopsy S showing reactivity with Lex (20-nm gold particles) and with Ley (10-nm gold particles).
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

8. Fig. 7
Immunoelectron microscopy of biopsy S showing an adhesion pedestal formation between gastric epithelial tissue and an H. pylori UA1182 cell. The Lex structures labeled are on both epithelial tissue and H. pylori (bar = 0.5 μm).
Gastroenterology  , DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions