1. Flowchart for calculating the relative risk (RR) for cancer X and lung cancer (LC).
Flowchart for calculating the relative risk (RR) for cancer X and lung cancer (LC). A family had four cancer patients (one LC patient and one cancer Y patient in the parental generation; one LC patient and one cancer X patient in the offspring). When RR for cancer X was calculated (left), the patient with cancer X in the offspring was used as the case for RR calculation and the two LC patients in first-degree relatives (FDRs) were used as probands. When RR for LC was calculated (the reverse analysis, right), the LC patient in the offspring was used as the case and the patient with cancer X in FDRs was used as proband.
Hongyao Yu et al. ERJ Open Res 2017;3:
©2017 by European Respiratory Society