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Summary findings regarding the efficacy/safety profile across xanthines in chronic obstructive pulmonary disease patients. a) Combined plot of the change from baseline in forced expiratory volume in 1 s (FEV1) and the risk of adverse events (AEs) of specifi... Summary findings regarding the efficacy/safety profile across xanthines in chronic obstructive pulmonary disease patients. a) Combined plot of the change from baseline in forced expiratory volume in 1 s (FEV1) and the risk of adverse events (AEs) of specific xanthine comparisons. b) Combined efficacy/safety SUCRA (surface under the cumulative ranking curve) analysis of specific xanthines. RE: relative effect; CrI: credible interval. Mario Cazzola et al. Eur Respir Rev 2018;27:180010 ©2018 by European Respiratory Society
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