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Has MRD monitoring superseded other prognostic factors in adult ALL?

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Presentation on theme: "Has MRD monitoring superseded other prognostic factors in adult ALL?"— Presentation transcript:

1 Has MRD monitoring superseded other prognostic factors in adult ALL?
by Monika Brüggemann, Thorsten Raff, and Michael Kneba Blood Volume 120(23): November 29, 2012 ©2012 by American Society of Hematology

2 Proposals for definition of MRD terms in ALL
Proposals for definition of MRD terms in ALL. Data from Brüggemann et al16 with permission. Proposals for definition of MRD terms in ALL. Data from Brüggemann et al16 with permission. Monika Brüggemann et al. Blood 2012;120: ©2012 by American Society of Hematology

3 Prospective therapeutic shifts according to conventional pretreatment stratification criteria and MRD. (A) Potential treatment decisions based on pretreatment factors. Prospective therapeutic shifts according to conventional pretreatment stratification criteria and MRD. (A) Potential treatment decisions based on pretreatment factors. (B) Potential treatment decisions based on MRD. Cons indicates consolidation; DLI, donor lymphocyte infusion; and TD, treatment decision. Monika Brüggemann et al. Blood 2012;120: ©2012 by American Society of Hematology


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