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Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study  John M. Brehm, MD, MPH, Brooke Schuemann, BS,

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Presentation on theme: "Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study  John M. Brehm, MD, MPH, Brooke Schuemann, BS,"— Presentation transcript:

1 Serum vitamin D levels and severe asthma exacerbations in the Childhood Asthma Management Program study  John M. Brehm, MD, MPH, Brooke Schuemann, BS, Anne L. Fuhlbrigge, MD, Bruce W. Hollis, PhD, Robert C. Strunk, MD, Robert S. Zeiger, MD, PhD, Scott T. Weiss, MD, MS, Augusto A. Litonjua, MD, MPH  Journal of Allergy and Clinical Immunology  Volume 126, Issue 1, Pages e5 (July 2010) DOI: /j.jaci Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Vitamin D levels and distributions by study center (A), season (B), and race (C). Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Sensitivity analysis of risk of hospitalization or ED visit by vitamin D level. The probabilities of severe exacerbations were plotted for the range of vitamin D levels in the study, and a smoothing function was used to draw a line through the values. Vertical lines represent quartiles of vitamin D levels. The risk of hospitalization starts to decrease around a vitamin D level of 30 ng/mL. Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Distribution of vitamin D levels at randomization in all subjects.
Journal of Allergy and Clinical Immunology  , e5DOI: ( /j.jaci ) Copyright © 2010 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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