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Vancomycin treatment is a risk factor for vancomycin-nonsusceptible Staphylococcus capitis sepsis in preterm neonates  M. Butin, J.-P. Rasigade, F. Subtil,

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Presentation on theme: "Vancomycin treatment is a risk factor for vancomycin-nonsusceptible Staphylococcus capitis sepsis in preterm neonates  M. Butin, J.-P. Rasigade, F. Subtil,"— Presentation transcript:

1 Vancomycin treatment is a risk factor for vancomycin-nonsusceptible Staphylococcus capitis sepsis in preterm neonates  M. Butin, J.-P. Rasigade, F. Subtil, P. Martins-Simões, C. Pralong, A.-M. Freydière, F. Vandenesch, S. Tigaud, J.-C. Picaud, F. Laurent  Clinical Microbiology and Infection  Volume 23, Issue 11, Pages (November 2017) DOI: /j.cmi Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2 Fig. 1 Case selection flow diagram. NICU, neonatal intensive care unit. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

3 Fig. 2 Time evolution of risk of Staphylococcus capitis late-onset sepsis in 222 intensive care neonates differentiated by (A, C) S. capitis colonization status at time t and/or (B, C) prior vancomycin treatment. At each time t after birth (x-axis), probability of subsequent S. capitis LOS (y-axis) was defined as number of patients who subsequently developed LOS divided by number of patients in group at time t (empty groups are not plotted). Patients with LOS at time t were excluded from analysis of subsequent time points. Patients with undetermined colonization status at time of S. capitis LOS (n = 7) were excluded from analysis. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions


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