Presentation is loading. Please wait.

Presentation is loading. Please wait.

Cellular Fatty Acid Metabolism and Cancer

Similar presentations


Presentation on theme: "Cellular Fatty Acid Metabolism and Cancer"— Presentation transcript:

1 Cellular Fatty Acid Metabolism and Cancer
Erin Currie, Almut Schulze, Rudolf Zechner, Tobias C. Walther, Robert V. Farese  Cell Metabolism  Volume 18, Issue 2, Pages (August 2013) DOI: /j.cmet Copyright © 2013 Elsevier Inc. Terms and Conditions

2 Figure 1 Overview of Cellular Fatty Acid Metabolism
See text for description of depicted pathways. Enzymes are in bold. Enzymes with boxes around them are membrane localized. Cell Metabolism  , DOI: ( /j.cmet ) Copyright © 2013 Elsevier Inc. Terms and Conditions

3 Figure 2 Model Showing How Limiting Fatty Acids in the Cell Might Limit Cancer Cell Proliferation This may be done by (1) blocking the synthesis of FA, (2) increasing the rate of FA degradation, (3) increasing FA storage in neutral TG, and/or (4) decreasing FA release from storage. Cell Metabolism  , DOI: ( /j.cmet ) Copyright © 2013 Elsevier Inc. Terms and Conditions


Download ppt "Cellular Fatty Acid Metabolism and Cancer"

Similar presentations


Ads by Google