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Thomas A. Waldmann, Sigrid Dubois, Yutaka Tagaya  Immunity 

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Presentation on theme: "Thomas A. Waldmann, Sigrid Dubois, Yutaka Tagaya  Immunity "— Presentation transcript:

1 Contrasting Roles of IL-2 and IL-15 in the Life and Death of Lymphocytes 
Thomas A. Waldmann, Sigrid Dubois, Yutaka Tagaya  Immunity  Volume 14, Issue 2, Pages (February 2001) DOI: /S (01)

2 Figure 1 Diagrammatic Model Outlining the Distinct Roles Played by IL-2 and IL-15 in the Life and Death of T Cells IL-2 is required for AICD involved in peripheral tolerance to self-antigen whereas IL-15 inhibits this process. In addition, IL-15 supports whereas IL-2 inhibits the survival of memory phenotype CD8+ T cells Immunity  , DOI: ( /S (01) )


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