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A randomized, double-blind, vehicle-controlled, bilateral comparison trial of bexarotene gel 1% versus vehicle gel in combination with narrowband UVB.

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Presentation on theme: "A randomized, double-blind, vehicle-controlled, bilateral comparison trial of bexarotene gel 1% versus vehicle gel in combination with narrowband UVB."— Presentation transcript:

1 A randomized, double-blind, vehicle-controlled, bilateral comparison trial of bexarotene gel 1% versus vehicle gel in combination with narrowband UVB phototherapy for moderate to severe psoriasis vulgaris  Melissa Amy Magliocco, MD, Komal Pandya, MD, RPh, Viktor Dombrovskiy, MD, PhD, MPH, Linda Christiansen, RN, Yuk Wong, RN, BSN, MA, Alice Bendix Gottlieb, MD, PhD  Journal of the American Academy of Dermatology  Volume 54, Issue 1, Pages (January 2006) DOI: /j.jaad Copyright © 2005 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Participant flow and follow-up.
Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2005 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 A, Target lesion score improvement in drug and placebo groups. (Percent reduction from initial score, mean ± SD.) Left (B) and right (C) posterior forearm target lesion at baseline. D, Left posterior forearm target lesion after drug treatment plus narrowband UVB (NBUVB). Lesion was flat, had minimal scale, and had slight macular erythema secondary to drug. E, Right posterior forearm target lesion after placebo treatment plus NBUVB. Residual scaling, erythema, and induration were present. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2005 American Academy of Dermatology, Inc. Terms and Conditions


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