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Volume 55, Issue 2, Pages (February 1999)

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Presentation on theme: "Volume 55, Issue 2, Pages (February 1999)"— Presentation transcript:

1 Volume 55, Issue 2, Pages 648-658 (February 1999)
Inflammation enhances cardiovascular risk and mortality in hemodialysis patients  Josef Zimmermann, Silke Herrlinger, Antje Pruy, Thomas Metzger, Christoph Wanner  Kidney International  Volume 55, Issue 2, Pages (February 1999) DOI: /j x Copyright © 1999 International Society of Nephrology Terms and Conditions

2 Figure 1 Frequency distribution of (A) C-reactive protein (CRP) and (B) serum amyloid A (SAA) in patients with end-stage renal disease treated with hemodialysis. Six percent of the patients exhibiting CRP levels between 70 and 152mg/liter were not depicted. Symbols are: (□) normal value; (▪) out of the normal range. Kidney International  , DOI: ( /j x) Copyright © 1999 International Society of Nephrology Terms and Conditions

3 Figure 2 Serum levels of Lp(a) in hemodialysis patients (HD) with elevated (A) CRP (more than 8mg/liter) and elevated (B) SAA (more than 10mg/liter) compared with patients with CRP and SAA in the normal range and healthy controls. In (A) symbols are: (□) healthy controls; () HD with CRP < 8mg/liter; (▪) HD with CRP> 8mg/liter. In (B) symbols are: (□) healthy controls; () HD with SAA < 10mg/liter; (▪) HD with SAA > 10mg/liter. Data are given as mean±sem. Abbreviations are: LMW, patients with low-molecular weight apo(a) isoforms (B, S1, S2); HMW, patients with high-molecular weight apo(a) isoforms (S3, S4, > S4). +P < 0.05; + +P < 0.01; + + +P < (vs. HD without activated acute phase). *P < 0.05; **P < 0.01; ***P < (vs. healthy controls). Kidney International  , DOI: ( /j x) Copyright © 1999 International Society of Nephrology Terms and Conditions

4 Figure 3 Kaplan-Meier estimates of survival during follow-up with regard to all-cause (A) and cardiovascular mortality (B) in relation to quartiles of serum concentrations of CRP. Kidney International  , DOI: ( /j x) Copyright © 1999 International Society of Nephrology Terms and Conditions

5 Kidney International 1999 55, 648-658DOI: (10. 1046/j. 1523-1755. 1999
Kidney International  , DOI: ( /j x) Copyright © 1999 International Society of Nephrology Terms and Conditions

6 Kidney International 1999 55, 648-658DOI: (10. 1046/j. 1523-1755. 1999
Kidney International  , DOI: ( /j x) Copyright © 1999 International Society of Nephrology Terms and Conditions

7 Kidney International 1999 55, 648-658DOI: (10. 1046/j. 1523-1755. 1999
Kidney International  , DOI: ( /j x) Copyright © 1999 International Society of Nephrology Terms and Conditions

8 Kidney International 1999 55, 648-658DOI: (10. 1046/j. 1523-1755. 1999
Kidney International  , DOI: ( /j x) Copyright © 1999 International Society of Nephrology Terms and Conditions

9 Kidney International 1999 55, 648-658DOI: (10. 1046/j. 1523-1755. 1999
Kidney International  , DOI: ( /j x) Copyright © 1999 International Society of Nephrology Terms and Conditions

10 Kidney International 1999 55, 648-658DOI: (10. 1046/j. 1523-1755. 1999
Kidney International  , DOI: ( /j x) Copyright © 1999 International Society of Nephrology Terms and Conditions


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