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Chasing Therapeutic Targets in Thymic Malignancies: Finding Needles in the Haystack to Frame a Comprehensive Canvas?  Nicolas Girard, MD  Journal of Thoracic.

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Presentation on theme: "Chasing Therapeutic Targets in Thymic Malignancies: Finding Needles in the Haystack to Frame a Comprehensive Canvas?  Nicolas Girard, MD  Journal of Thoracic."— Presentation transcript:

1 Chasing Therapeutic Targets in Thymic Malignancies: Finding Needles in the Haystack to Frame a Comprehensive Canvas?  Nicolas Girard, MD  Journal of Thoracic Oncology  Volume 11, Issue 8, Pages (August 2016) DOI: /j.jtho Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 Therapeutic targeting of the hallmarks of thymic carcinomas. KIT, KIT proto-oncogene receptor tyrosine kinase; CDKN2A/B, cyclin-dependent kinase inhibitor 2A/B; IGF-R, insulin-like growth factor 1 receptor; PD-L1, programmed death ligand-1; PI3K, phosphoinositide-3-kinase; BCL2, B-cell lymphoma 2; VEGFR, vascular endothelial growth factor receptor. (Adapted with permission from Hanahan and Weinberg.8) Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

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