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Volume 140, Issue 2, Pages (January 2010)

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1 Volume 140, Issue 2, Pages 176-178 (January 2010)
Forever Young  Leonard Guarente  Cell  Volume 140, Issue 2, Pages (January 2010) DOI: /j.cell Copyright © 2010 Elsevier Inc. Terms and Conditions

2 Figure 1 Keeping Daughters Youthful
Depicted is the retrograde flow of damaged protein aggregates along actin cables from the daughter bud to the mother cell during budding in yeast. CCT and Sir2p fold actin to provide the substrate for cable formation. Myo2p transports material into the bud for growth. Hsp104 binds to damaged protein aggregates to ensure their retrograde transport out of buds along actin cables. Cell  , DOI: ( /j.cell ) Copyright © 2010 Elsevier Inc. Terms and Conditions

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