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Signal Transduction Pathways and Cell Differentiation

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Presentation on theme: "Signal Transduction Pathways and Cell Differentiation"— Presentation transcript:

1 Signal Transduction Pathways and Cell Differentiation
Stem Cell Specialized cell type (neuron, skin cell, red blood cell, etc.)

2 Blood Cell Formation

3 Red Blood Cell Development

4 EPO Synthesis of proteins that stimulate Red Blood Cell development

5 Negative Regulation of JAK/STAT Pathway

6 Microtubules

7 Tubulin Dimer GTP GTP

8

9 Centrosome Structure

10

11

12 Pg. 583

13

14 Microtubule “Poisons”
Colchicine Taxol (Autumn crocus) (Pacific Yew)

15 Tubulin Dimer GTP GTP Taxol

16 Microtubule “Motor” Proteins

17

18 Microtubule “Motor” Proteins

19 Microtubules Help to Organize the Cytoplasm

20

21

22 Actin Filaments

23 Actin Monomer

24

25 Arp2/3 (Actin Related Proteins)

26

27 Actin-GFP Actin Cable Cortical Actin Patch

28 Actin Cables and Actin Patches

29 Thrombin Resting Platlet Activated Platlet

30

31 Gelsolin Protein New minus end

32

33

34 Myosin-II

35 Muscle Cell

36 Sarcomere

37 Contraction of a Sarcomere

38 Resting Muscle

39

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