1. Advancing Acute Coronary Syndrome Assessment:

2. Goals

3. ED Visits - United States

4. Approach to Evaluation

5. Temporal Rise and Fall of Existing Necrosis Biomarkers

7. What is a Great Troponin Assay?

10. Making it More Sensitive The New Era of Troponin Use

11. Early Diagnosis of Myocardial Infarction With Sensitive Cardiac Troponin Assays

12. Rapid Exclusion of Acute Myocardial Infarction in Patients With Undetectable Troponin Using a High-sensitivity Assay

13. Increasingly Sensitive Assays for Cardiac Troponins A Review

14. Noise vs Signal The Clinical Implications of an Increasingly Sensitive Troponin Assay for Patients With Suspected Acute Coronary Syndrome

18. Utility of Absolute and Relative Changes in Cardiac Troponin Concentrations in the Early Diagnosis of Acute Myocardial Infarction

19. TRAPID-AMI Results Presented at ESC 2014

21. Validation of High-sensitivity Troponin I in a 2-hour Diagnostic Strategy to Assess 30-day Outcomes in Emergency Department Patients With Possible Acute Coronary Syndrome

22. Algorithm - Admit or Discharge

23. Relative Differences in Serial Troponin Measurement

24. Absolute Differences in Serial Troponin Measurement

25. Incremental Value of Copeptin for Rapid Rule Out of Acute Myocardial Infarction

26. Summary

27. Abbreviations

28. Abbreviations (cont)

29. References

30. References (cont)

31. References (cont)

32. References (cont)