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A Case of Concurrent De Novo C797S and L858R EGFR Mutation Detected in Stage IA Non–Small Cell Lung Cancer Patient  Jong Sik Lee, MD, Jae Young Hur, PhD,

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Presentation on theme: "A Case of Concurrent De Novo C797S and L858R EGFR Mutation Detected in Stage IA Non–Small Cell Lung Cancer Patient  Jong Sik Lee, MD, Jae Young Hur, PhD,"— Presentation transcript:

1 A Case of Concurrent De Novo C797S and L858R EGFR Mutation Detected in Stage IA Non–Small Cell Lung Cancer Patient  Jong Sik Lee, MD, Jae Young Hur, PhD, Hee Joung Kim, MD, PhD, Kye Young Lee, MD, PhD  Journal of Thoracic Oncology  Volume 12, Issue 11, Pages e179-e181 (November 2017) DOI: /j.jtho Copyright © Terms and Conditions

2 Figure 1 Serial interval low-dose computed tomography (LDCT) scans of patient with de novo C797S mutation. (A) An 8.6-mm ground glass opacity in the left lower lobe was observed on an LDCT scan in March (B) Follow-up LDCT scan in January (C) Follow-up LDCT scan in March (D) A 12.6-mm ground glass opacity is displayed on a follow-up LDCT scan in March 2017. Journal of Thoracic Oncology  , e179-e181DOI: ( /j.jtho ) Copyright © Terms and Conditions

3 Figure 2 Tissue and pyrograms obtained from the patient. (A) Histopathologic section shows adenocarcinoma with a predominant acinar pattern (hematoxylin and eosin stain; original magnification, ×100). (B) Pyrograms from adenocarcinoma show EGFR exon 20 C797S mutation and EGFR exon 21 L858R mutation. (C) Pyrograms from adjacent normal lung show a wild-type sequence. Journal of Thoracic Oncology  , e179-e181DOI: ( /j.jtho ) Copyright © Terms and Conditions

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