1. Effect of Aspergillus fumigatus and Candida albicans on pro-inflammatory response in cystic fibrosis epithelium 
James A. Reihill, John E. Moore, J. Stuart Elborn, Madeleine Ennis 
Journal of Cystic Fibrosis 
Volume 10, Issue 6, Pages (December 2011)
DOI: /j.jcf
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2. Fig. 1
Cytokine release from Candida albicans-treated HBE and CFBE. HBE (filled diamonds) and CFBE (filled squares) were treated with varying doses of Candida albicans whole cells as indicated for 24h then IL-6 (A) and IL-8 (B) levels determined by ELISA (n=5). Treatment of cells with cytomix (positive control) gave the following values HBE IL ±305pg/ml, IL ±117pg/ml CFBE: IL ±322pg/ml, IL ±236pg/ml (data not shown) (C). THP-1 cells were treated with an equal ratio (1:1) of Candida albicans whole cells (n=3) or Aspergillus fumigatus conidia (n=3) for 24h then IL-8 was assessed by ELISA. Treatment of THP-1 cells with cytomix gave the following: 1083±114.9pg/ml. *p<0.05 compared with basal.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
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3. Fig. 2
Cytokine release from Aspergillus fumigatus-treated HBE and CFBE. HBE (filled diamonds) and CFBE (filled squares) were treated with varying doses of Aspergillus fumigatus conidia as indicated for 24h then IL-6 (A) and IL-8 (B) levels determined by ELISA. Data shown in A and B is representative of at least 6 independent experiments. Treatment of cells with cytomix resulted in the following cytokine levels HBE IL ±236pg/ml, IL ±116pg/ml CFBE: IL ±335pg/ml, IL ±310pg/ml. (C) HBE or CFBE were treated with varying doses of Aspergillus fumigatus conidia then LDH levels were measured (n=3). A 1% v/v LDH solution in culture media served as a positive control. *p<0.05 **p<0.01 compared with basal.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf )
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