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Protective antibody responses to pneumococcal conjugate vaccine after autologous hematopoietic stem cell transplantation  Joseph H. Antin, Eva C. Guinan,

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Presentation on theme: "Protective antibody responses to pneumococcal conjugate vaccine after autologous hematopoietic stem cell transplantation  Joseph H. Antin, Eva C. Guinan,"— Presentation transcript:

1 Protective antibody responses to pneumococcal conjugate vaccine after autologous hematopoietic stem cell transplantation  Joseph H. Antin, Eva C. Guinan, David Avigan, Robert J. Soiffer, Robin M. Joyce, Victoria J. Martin, Deborah C. Molrine  Biology of Blood and Marrow Transplantation  Volume 11, Issue 3, Pages (March 2005) DOI: /j.bbmt Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Effect of immunization with heptavalent pneumococcal conjugate vaccine (PCV7) before stem cell collection on antibody responses to PCV7 administered after autoHCT. Geometric mean IgG antibody concentrations to the serotypes of PCV7 of patients immunized with PCV7 before stem cell collection (—) were compared with those of patients not immunized before stem cell collection (- - -). As indicated by the arrowheads, all study patients received PCV7 3, 6, and 12 months after autoHCT. *Geometric mean antibody concentrations were significantly higher for the group immunized before stem cell collection compared with those not immunized before stem cell collection (P ≤ .05; t test). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions


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