1. Announcements
Turn in your “I am a _________ cell” information with name on back side and definition of “homeostasis.”
Personal info (voluntary) due Friday
Group pictures in lab this week
Switch to Tuesday Morning Lab?
Community of Scholars Research Symposium
Saturday Sept 11 from 9- noon
10 weeks paid research on topic of your choosing!
Summer 2011?

2. Why are CBCs so important to physicians and their patients?
1QQ # 1
Name on top edge, back side of paper
Answer on blank side of paper.
Answer one of the following:
The 200+ cell types in the human body can be classified into one of 4 cell types or tissue types. List 3 of the 4 types.
List as many items that you can think of that are measured and reported in a CBC (complete blood count.)
Why are CBCs so important to physicians and their patients?

3. A Taxonomy of Cognitive Skills for Developing Student Assignments and Assessments*
*SC SDE (Pat Mohr). Adapted from Lorin W. Anderson, David R. Krathwohl et al (Eds.) A Taxonomy for Learning, Teaching, and Assessing: A Revision of Bloom’s Taxonomy of Educational Objectives  2001; modified by Ellen Goldey, Wofford College, to incorporate “Biology in Bloom,” Crowe et al., 2008, CBE – Life Sci Edu., 7:
**HOCS = higher order cognitive skills, LOCS = lower order cognitive skills.
Cognitive Domain (Revised Bloom)
Description
Action verbs
Original Bloom’s term
1.Remember (LOCS)**
Retrieve relevant knowledge
Recognize, identify, recall, list, label
Knowledge
2. Understand (LOCS)
Describe meaning
Interpret, exemplify, classify, summarize/
explain/describe in own words
Comprehension
3. Apply (LOCS/HOCS)
Use/apply procedures or info in novel context
Execute, predict
Application
4. Analyze (HOCS)
Infer relationships between components or parts and bigger picture
Differentiate, organize, link, attribute, infer, interpret, diagnose, compare/contrast, conclude, speculate
Analysis
5. Evaluate (HOCS)
Make judgments based on evidence, criteria, and standards
Verify, critique, assess merit
Evaluation
6. Create (HOCS)
Piece together info to form novel whole; create original product
Generate, plan, build, produce, design, model
Synthesis

4. The body: A society of interdependent cells, each type with its own needs and contributions.
01.01a.jpg

5. The Human Body: A Society of Cells
Imagine you are a cell. Ask yourself:
How did I get here? 
What do I do for myself? (What are my special characteristics and functions?) 
What do I do for the person in whom I reside? (What are my contributions to the whole organism? To homeostasis?) 
What do I need simply to survive?
What do the other cells provide for me that I cannot obtain alone?
What governs my actions? 
How long will I live?
Can I be replaced? If so, how?
What would happen to the organism if I along with all the other cells of my type were to fail to function properly?

6. O2 pH
CO2
Temp,
[glucose],
[Na+], [K+], [Ca++], amino acids
Nucleic acids

7. Cell Membrane: selectively permeable
Capillaries: highly permeable except to proteins

8. Beggar Thessaloniki, Greece
Homeostasis:
The relative constancy of the internal environment
Steady state vs. equilibrium
Beggar Thessaloniki, Greece

9. Street vendor Thessaloniki, Greece
Homeostasis:
The relative constancy of the internal environment
Steady state vs. equilibrium
Street vendor Thessaloniki, Greece

10. San woman Kalahari Desert, Botswana
Homeostasis:
The relative constancy of the internal environment
Steady state vs. equilibrium
San woman Kalahari Desert, Botswana

11. Camp’s Bay Beach, Cape Town, South Africa
Homeostasis:
Camp’s Bay Beach, Cape Town, South Africa

12. Phillip cooling off in waterfall, Vietnam
Homeostasis:
Phillip cooling off in waterfall, Vietnam

13. ~37oC

14. Homeostasis
Regulated via reflex arcs and naturally maintained by the process of negative feedback
Measurement
Which physiological variables?
Averages and ranges

15. Fig. 01.08 Diurnal cycles Awake Awake Sleep Sleep
01.08.jpg
Major point: Set points are not absolute!

16. An example of homeostasis by negative feedback.
Thermoregulation
An example of homeostasis by negative feedback.

17. The Challenge:
# 1: Melt these 7 ice cubes as fast as possible. How to do it?
# 2: Make these 7 ice cubes last as long as possible? How to do it?
These are non-living objects: heat exchanges with the environment but they don’t generate heat from metabolism as living things do!

18. ~37oC Conduction Convection Evaporation Radiation
Metabolism generates heat. Metabolism is variable!
In steady state: Heat gain = Heat loss

19. ~37oC Modes of Heat Exchange:
Conduction Convection Radiation Evaporation
~37oC

20. ~37oC Modes of Heat Exchange:
Conduction Convection Radiation Evaporation
~37oC

21. ~37oC Modes of Heat Exchange:
Conduction Convection Radiation Evaporation
~37oC