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Homeostasis Dr. Sadaf Mumtaz 29/11/11
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AIMS Introduction to Physiology Levels of Organization in the body
Homeostasis Homeostatic control systems
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What is Physiology?
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Levels of organization in the body
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Homeostasis Homeo means ‘the same’; and stasis means ‘to stand or stay’ Maintenance of ‘a relatively or nearly’ stable internal enviroment
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Significance of internal Enviroment
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Differences between ECF & ICF
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Contribution of body systems in maintaining homeostasis
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Homeostatic control systems
Grouping of control systems Intrinsic Extrinsic Negative and positive feedback and feedforward mechanisms
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Properties of control systems
The direction of correction will be always towards stability. After the error is sensed, there is a delay in onset of correction. The correction is proportional to the magnitude of error.
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The effectiveness of a particular control system can be assessed by the calculation of gain
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1. Blood pressure= 100 to 175mmHg
Correction = Adjustment – Abnormal increase = 125 – 175 = -50 Error = 25 Gain = Correction/Error = -50/25 = -2 2. Blood pressure= 100 to 175mmHg = 105 – 175 = -70 Error = 5 = -70/5 = -14
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Negative feedback
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Positive feedback
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Feedforward mechanism
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Thanks
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Performance based on knowledge
Temperature Roll number 1-30 Blood pressure Exercise Digestion
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