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Table 1. Criteria for differentiating acute and chronic hepatitis C

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1 Table 1. Criteria for differentiating acute and chronic hepatitis C
Stage Definition Acute Recent HCV seroconversion (prior negative test for hepatitis C in last 12 months) or Detection of hepatitis C virus nucleic acid (HCV RNA) or hepatitis C virus core antigen (HCV-core) in serum/plasma and no detection of hepatitis C virus antibody (negative result) Chronic Detection of hepatitis C virus nucleic acid (HCV RNA) or hepatitis C core antigen (HCV-core) in serum/plasma in two samples taken at least 12 months apart* Unknown Any newly diagnosed case which cannot be classified in accordance with the above definition of acute or chronic infection Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report Hepatitis C. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, Reproduction is authorised, provided the source is acknowledged

2 Table 2. Number and rate of reported hepatitis C cases per 100 000 population, EU/EEA, 2010–2014†
2010 2011 2012 2013 2014 Country All Acute* Chronic* Unknown* Cases Rate Austria 880 10.5 1122 13.4 1075 12.8 993 11.7 1954 23 93 1.1 913 10.7 948 11.1 Belgium 1151 Bulgaria 58 0.8 60 92 1.3 95 90 1.2 Croatia 171 4 202 4.7 144 3.4 Cyprus 26 3.2 57 6.8 48 5.6 36 4.2 30 3.5 Czech Republic 709 812 7.7 796 7.6 929 8.8 808 Denmark 318 5.7 295 5.3 263 265 181 6 0.1 173 3.1 2 Estonia 276 20.7 210 15.8 245 18.5 273 315 23.9 20 1.5 22.4 Finland 1138 21.3 1135 21.1 1165 21.6 1172 1224 22.5 France Germany 5281 6.5 5075 6.2 4978 6.1 5168 6.3 5737 7.1 Greece 11 18 0.2 43 0.4 22 <0.1 16 Hungary 38 46 0.5 Iceland 59 18.6 72 22.6 51 Ireland 1240 27.3 1254 27.4 1026 778 16.9 694 15.1 21 68 605 13.1 Italy 236 234 221 205 0.3 45 Latvia 1156 54.5 1324 63.8 1352 66.1 1327 65.6 1491 74.5 2.8 1434 71.6 Lithuania 41 1.4 40 34 Luxembourg 73 14.5 74 53 10.1 12.7 12.4 Malta 14 4.3 24 3.3 1 13 Netherlands 31 65 52 Norway 1783 36.7 1675 1513 30.3 1318 26.1 1213 23.7 Poland 2179 2241 5.9 2265 2641 6.9 3551 9.3 Portugal 39 42 63 0.6 7 56 Romania 76 80 126 127 104 84 Slovakia 237 4.4 304 230 314 5.8 381 35 346 6.4 Slovenia 87 4.6 102 5 89 64 3 61 Spain Sweden 1939 20.8 2153 22.9 1990 2005 1786 United Kingdom 9951 15.9 12138 19.3 13474 21.2 13757 21.5 14028 21.8 1291 12737 19.8 Total EU/EEA 27849 7.3 30645 8 31480 8.1 32061 8.3 35321 458 4698 3.7 26380 9.5 † Data presented by date of diagnosis. * Includes the cases reported by countries as acute, chronic or unknown using the differentiation criteria Source: Country reports Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report Hepatitis C. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, Reproduction is authorised, provided the source is acknowledged

3 Figure 1. Rate of acute and chronic hepatitis C cases per 100 000 population, EU/EEA, 2006–2014
Source: Country reports from Austria, Belgium, Bulgaria, Croatia, Cyprus, the Czech Republic, Denmark, Estonia, Finland, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, Sweden, and the United Kingdom. Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report Hepatitis C. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, Reproduction is authorised, provided the source is acknowledged

4 Figure 2. Rate of reported acute hepatitis C cases per 100 000 population, EU/EEA, 2014
Source: Country reports from Austria, Bulgaria, Croatia, Cyprus, the Czech Republic, Denmark, Estonia, Finland, Germany, Greece, Iceland, Ireland, Italy, Latvia, Luxembourg, Malta, Norway, Poland, Romania, Slovakia, Slovenia, Sweden, and the United Kingdom. Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report Hepatitis C. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, Reproduction is authorised, provided the source is acknowledged

5 Figure 3. Rate of reported hepatitis C cases per 100 000 population, by age and gender, EU/EEA, 2014
Source: Country reports from Austria, Belgium, Bulgaria, Croatia, Cyprus, the Czech Republic, Denmark, Estonia, Finland, Germany, Greece, Hungary, Iceland, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Sweden, and the United Kingdom. Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report Hepatitis C. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, Reproduction is authorised, provided the source is acknowledged

6 Figure 4. Transmission category of hepatitis C cases by acute and chronic disease status, EU/EEA, 2014 Source: Country reports from Austria, Denmark, Estonia, Greece, Hungary, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Portugal, Romania, Slovakia, Slovenia, and the United Kingdom. Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report Hepatitis C. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, Reproduction is authorised, provided the source is acknowledged

7 Table. Hepatitis C, surveillance systems overview, 2014
Surveillance Data reported by Case definition used characteristics Country Data source L P H O Austria AT-Epidemiegesetz Co C Y EU-2008 Belgium BE-LABNET Se N . Other Bulgaria BG-NATIONAL_SURVEILLANCE Croatia HR-CNIPH A EU-2012 Cyprus CY-NOTIFIED_DISEASES Czech Republic CZ-EPIDAT Denmark DK-MIS Estonia EE-NAKIS Finland FI-NIDR Germany Greece EL-NOTIFIABLE_DISEASES Hungary HU-EFRIR Iceland IS-SUBJECT_TO_REGISTRATION Ireland IE-CIDR Italy IT-NRS IT-SEIEVA Latvia LV-BSN Lithuania LT-COMMUNICABLE_DISEASES Luxembourg LU-SYSTEM1 Malta MT-DISEASE_SURVEILLANCE Netherlands NL-OSIRIS Norway NO-MSIS_A Poland PL-NATIONAL_SURVEILLANCE Portugal PT-HEPATITISC Romania RO-RNSSy Slovakia SK-EPIS Slovenia SI-SURVIVAL Sweden SE-SMINET United Kingdom UK-HEPATITISC Surveillance characteristics: compulsory (Cp), comprehensive (co), voluntary (V), other (O), active (A), passive (P), case-based (C), aggregated (A) Data reported by: laboratories (L), physicians (P), hospitals (H), other (O) Suggested citation: European Centre for Disease Prevention and Control. Annual epidemiological report Hepatitis C. Stockholm: ECDC; 2016. © European Centre for Disease Prevention and Control, Reproduction is authorised, provided the source is acknowledged

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