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Volume 93, Issue 4, Pages (April 2018)

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1 Volume 93, Issue 4, Pages 941-951 (April 2018)
Primary outcomes of the Monitoring in Dialysis Study indicate that clinically significant arrhythmias are common in hemodialysis patients and related to dialytic cycle  Prabir Roy-Chaudhury, Jim A. Tumlin, Bruce A. Koplan, Alexandru I. Costea, Vijay Kher, Don Williamson, Saurabh Pokhariyal, David M. Charytan Don Williamson, Prabir Roy-Chaudhury, James Tumlin, Vijay Kher, Vikranth Reddy, Kowdle Chandrasekhar Prakash, David Charytan, Suresh Chandra Tiwari, Saurabh Pokhariyal, Amber Podoll, Sanjeev Jasuja, G. Leslie Walters, Kraig Wangsnes, Alexandru Costea, Selcuk Tombul, Balbir Singh, Brajesh Mishra, Sachin Yalagudri, Abhijeet Shelke, Calambur Narasimhan, A.M. Karthigesan, Abraham Oomman, K.P. Pramod Kumar, Bruce Koplan, Upendra Kaul, Tapan Ghose, Ripen Gupta, Arvind Sethi, Nikhil Kumar, Ramesh Hariharan, Rajnish Sardana, Arif Wahab, N.N. Khanna, Mark Smith, Suresh Kamath, Claude Galphin, Puneet Sodhi, Rajsekara Chakravarthy, Subba Rao Budithi, Finnian McCausland, Sanjeev Gulati, Munawer Dijoo, Upendra Singh, Salil Jain, Vishal Saxena, Gaurav Sagar, David Charytan, Rachel Fissell, Robert Foley, Charles A. Herzog, Peter McCullough, John D. Rogers, James A. Tumlin, Peter Zimetbaum, Manish Assar, Mark Kremers, Wolfgang C. Winkelmayer Prabir Roy-Chaudhury, Jim A. Tumlin, Bruce A. Koplan, Alexandru I. Costea, Vijay Kher, Don Williamson, Saurabh Pokhariyal, David M. Charytan Don Williamson, Prabir Roy-Chaudhury, James Tumlin, Vijay Kher, Vikranth Reddy, Kowdle Chandrasekhar Prakash, David Charytan, Suresh Chandra Tiwari, Saurabh Pokhariyal, Amber Podoll, Sanjeev Jasuja, G. Leslie Walters, Kraig Wangsnes, Alexandru Costea, Selcuk Tombul, Balbir Singh, Brajesh Mishra, Sachin Yalagudri, Abhijeet Shelke, Calambur Narasimhan, A.M. Karthigesan, Abraham Oomman, K.P. Pramod Kumar, Bruce Koplan, Upendra Kaul, Tapan Ghose, Ripen Gupta, Arvind Sethi, Nikhil Kumar, Ramesh Hariharan, Rajnish Sardana, Arif Wahab, N.N. Khanna, Mark Smith, Suresh Kamath, Claude Galphin, Puneet Sodhi, Rajsekara Chakravarthy, Subba Rao Budithi, Finnian McCausland, Sanjeev Gulati, Munawer Dijoo, Upendra Singh, Salil Jain, Vishal Saxena, Gaurav Sagar, David Charytan, Rachel Fissell, Robert Foley, Charles A. Herzog, Peter McCullough, John D. Rogers, James A. Tumlin, Peter Zimetbaum, Manish Assar, Mark Kremers, Wolfgang C. Winkelmayer  Kidney International  Volume 93, Issue 4, Pages (April 2018) DOI: /j.kint Copyright © 2017 International Society of Nephrology Terms and Conditions

2 Figure 1 Flow of patients in the Monitoring in Dialysis (MiD) trial. *Study was complete when last implanted patient completed 6 months of follow-up. LTFU, long-term follow-up. Kidney International  , DOI: ( /j.kint ) Copyright © 2017 International Society of Nephrology Terms and Conditions

3 Figure 2 Temporal patterns of arrhythmias relative to the weekly dialytic cycle. (a) Clinically significant arrhythmia. (b) Clinically significant bradycardia. (c) Atrial fibrillation. Temporal patterns of arrhythmia relative to weekly dialytic cycle. Only the subjects with a Monday-Wednesday-Friday or Tuesday-Thursday-Saturday session pattern and the weeks with 3 sessions and without any off-schedule sessions were included. Asterisks indicate P value < 0.05 for pairwise comparison with reference nadir 24 to 36 hours after third weekly dialysis session. HD1 through HD3 indicate the first through third hemodialysis (HD) sessions of the week (blue, red, and green, respectively). Numbers below the graph refer to the number of hours after the prior dialysis session. Error bars show the lower bound of the 95% confidence interval. Kidney International  , DOI: ( /j.kint ) Copyright © 2017 International Society of Nephrology Terms and Conditions

4 Figure S1 Screening and enrollment of US subjects.
Kidney International  , DOI: ( /j.kint ) Copyright © 2017 International Society of Nephrology Terms and Conditions

5 Figure S2 Screening and enrollment of subjects in India.
Kidney International  , DOI: ( /j.kint ) Copyright © 2017 International Society of Nephrology Terms and Conditions


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