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Long-Term Management of Overactive Bladder with Antimuscarinic Agents

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Presentation on theme: "Long-Term Management of Overactive Bladder with Antimuscarinic Agents"— Presentation transcript:

1 Long-Term Management of Overactive Bladder with Antimuscarinic Agents
Christian Hampel  European Urology Supplements  Volume 6, Issue 5, Pages (March 2007) DOI: /j.eursup Copyright © Terms and Conditions

2 Fig. 1 Treatment persistence rates over time in 231 women with detrusor instability or low compliance on antimuscarinic therapy. Numbers over bars represent number of women receiving therapy at each time point [1]. European Urology Supplements 2007 6, DOI: ( /j.eursup ) Copyright © Terms and Conditions

3 Fig. 2 Treatment persistence, patient compliance and drug-switching rates after 12 mo of therapy with tolterodine or oxybutinin. ***p<0.001 vs. oxybutinin; †patients switching to alternative agents for treatment of overactive bladder [4]. European Urology Supplements 2007 6, DOI: ( /j.eursup ) Copyright © Terms and Conditions

4 Fig. 3 Mean rates of compliance with therapy as daily dose frequency increases. *p<0.01, **p<0.001 vs. once-daily dosing [11]. European Urology Supplements 2007 6, DOI: ( /j.eursup ) Copyright © Terms and Conditions

5 Fig. 4 Adverse events reported in randomised clinical trials of antimuscarinic agents 1996–2004. Reprinted from Chapple C, Khullar V, Gabriel Z, et al. The effects of antimuscarinic treatments in overactive bladder: a systematic review and meta-analysis. Eur Urol 2005;48:5–26, © 2005, with permission from the European Association of Urology. European Urology Supplements 2007 6, DOI: ( /j.eursup ) Copyright © Terms and Conditions


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