1. The temporal dynamics of switch between hippocampal attractor states
Karel Jezek
CBM, Trondheim
Lab meeting, 13.October, 2008

2. how does the HP/EC system toggle between multiple spatial maps?
hippocampal spatial representation is discontinuous
and
our perception of the surrounding world as well
a basic need to flexibly update the orientation system
whenever the sensory inputs do not match with the active representation
how does the HP/EC system toggle between multiple spatial maps?

3. pretraining

4. pretraining

5. testing

6. testing
TELEPORT TASK

7. example of recorded CA3 units population
sleep A B

8. reference population vectors (expected activity)B A B

9. test population vectors
fissure eeg 6-12 Hz

10. example of 20 sec. running in environments A and B

11. map overlap is expressed within single theta cycle
P-correlation coeff.
Cells 1...n
fissure eeg 6-12 Hz
seconds

12. Patterns of remapping - state alternation
TELEPORTATION
24 sec. B A

13. Alternation between states correlation plots3 8
Alternation between states correlation plots
Animal running in env. A, transiently activating the representation for B
each frame represents population activity within one theta cycle
pink dot- animal’s current position 4 9 5 10 B A 1 6 11 2 7 12

14. Transitions between maps
in the “teleportation” experiment (Jezek et al, 2011)

15. Towards episodic memory
(De Lavilleon et al 2015)