1. Progressive Multifocal Leukoencephalopathy
Melissa M. Blessing, DO, Aditya Raghunathan, MD, Lori A. Erickson, MD 
Mayo Clinic Proceedings 
Volume 93, Issue 1, Pages (January 2018)
DOI: /j.mayocp
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2. Figure
These photomicrographs of the cerebellum demonstrate the “histopathologic triad” of PML as well as in situ evidence of infection. A and B, Numerous “bizarre” astrocytes (closed arrows) and a viral nuclear inclusion (open arrow) in an enlarged oligodendryocyte are seen in a background of macrophages. C, Myelin stain (LFB/PAS) shows extensive demyelination with pale white matter instead of normal dark blue white matter. D, In situ hybridization for JC virus DNA is positive in infected cells (closed arrows), confirming the diagnosis. JC = John Cunningham; LFB = Luxol fast blue; PAS = Periodic acid–Schiff.
Mayo Clinic Proceedings  , DOI: ( /j.mayocp )
Copyright © 2017 Mayo Foundation for Medical Education and Research Terms and Conditions

3. Mayo Clinic Proceedings 2018 93, 123-125DOI: (10. 1016/j. mayocp. 2017
Copyright © 2017 Mayo Foundation for Medical Education and Research Terms and Conditions