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Oral application of bacterial lysate in infancy decreases the risk of atopic dermatitis in children with 1 atopic parent in a randomized, placebo-controlled.

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Presentation on theme: "Oral application of bacterial lysate in infancy decreases the risk of atopic dermatitis in children with 1 atopic parent in a randomized, placebo-controlled."— Presentation transcript:

1 Oral application of bacterial lysate in infancy decreases the risk of atopic dermatitis in children with 1 atopic parent in a randomized, placebo-controlled trial  Susanne Lau, MD, PhD, Kerstin Gerhold, MD, PhD, Kurt Zimmermann, PhD, Charlotte W. Ockeloen, MD, Siri Rossberg, MD, Petra Wagner, Claudia Sulser, MD, Rita Bunikowski, MD, Imke Witt, MD, Juliane Wauer, MD, John Beschorner, MD, Georg Menke, PhD, Eckard Hamelmann, MD, PhD, Ulrich Wahn, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 129, Issue 4, Pages (April 2012) DOI: /j.jaci Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Study design. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Flow chart of study participants (light gray, intervention phase; green, follow-up phase). Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig 3 Total study group with double and single parental heredity (n = 606): eczema-free survival rates in the active and placebo intervention groups up to 3 years of life (ITT evaluation). Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5 Fig 4 Single parental heredity subgroup (either in the mother or the father, n = 296): eczema-free survival rates in the active and placebo intervention groups up to 3 years of life (ITT evaluation). Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions


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