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DNA Structure & Replication
AP Biology DNA Structure & Replication
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Nucleic Acid Structure
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Complimentary Base Pairing
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S Phase of Cell Cycle
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Theta Replication in Prokaryotes
Replication fork Origin of replication Termination of replication
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Linear Replication in Eukaryotes
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The parent molecule has two complementary
. The parent molecule has two complementary strands of DNA. Each base is paired by hydrogen bonding with its specific partner, A with T and G with C.
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The parent molecule has two complementary
. The parent molecule has two complementary strands of DNA. Each base is paired by hydrogen bonding with its specific partner, A with T and G with C. The first step in replication is separation of the two DNA strands.
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Semi Conservative process of DNA Replication
The parent molecule has two complementary strands of DNA. Each base is paired by hydrogen bonding with its specific partner, A with T and G with C. The first step in replication is separation of the two DNA strands. Each parental strand now serves as a template that determines the order of nucleotides along a new, complementary strand.
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Origins and Replication bubbles
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DNA Replication
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DNA Replication by adding Nucleosides on the 3’ end
New strand Template strand 5¢ end 3¢ end 5¢ end 3¢ end Sugar Base Phosphate DNA polymerase 3¢ end 3¢ end Pyrophosphate Nucleoside triphosphate 5¢ end 5¢ end
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5 Carbon Sugar Important Parts (It could be DNA or RNA)
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Helicase is the GREEN “blob”
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RNA Primer (Remember, RNA is temporary)
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DNA polymerase Pyrophosphate Nucleoside triphosphate
. New strand Template strand 5¢ end 3¢ end 5¢ end 3¢ end Sugar Base Phosphate DNA polymerase 3¢ end 3¢ end Pyrophosphate Nucleoside triphosphate 5¢ end 5¢ end
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Nucleotide Excision Repair
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Telomere Removal at the Chromosome Ends
5¢ End of parental DNA strands Leading strand Lagging strand 3¢ Last fragment Previous fragment RNA primer Lagging strand 5¢ 3¢ Primer removed but cannot be replaced with DNA because no 3¢ end available for DNA polymerase Removal of primers and replacement with DNA where a 3¢ end is available 5¢ 3¢ Second round of replication 5¢ New leading strand 3¢ New leading strand 5¢ 3¢ Further rounds of replication Shorter and shorter daughter molecules
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Apoptosis in the hand
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