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A Time to Divide: Does the Circadian Clock Control Cell Cycle?

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Presentation on theme: "A Time to Divide: Does the Circadian Clock Control Cell Cycle?"— Presentation transcript:

1 A Time to Divide: Does the Circadian Clock Control Cell Cycle?
Jacqueline A. Walisser, Christopher A. Bradfield  Developmental Cell  Volume 10, Issue 5, Pages (May 2006) DOI: /j.devcel Copyright © 2006 Elsevier Inc. Terms and Conditions

2 Figure 1 Clocks, Clock-Controlled Genes, and Cell Cycle Decisions
Altered expression of Period genes (Per2 deficiency or Per1 overexpression) appears to mediate cell fate decisions (cancer, apoptosis) through regulation of the expression of various clock-controlled genes involved in cell cycle regulation and DNA damage control. Whether the Period genes, known core circadian clock components, act through disruption of the circadian clock or through a clock-independent mechanism (question marks) is still unclear. Developmental Cell  , DOI: ( /j.devcel ) Copyright © 2006 Elsevier Inc. Terms and Conditions

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