Presentation is loading. Please wait.

Presentation is loading. Please wait.

Clinical Microbiology and Infection

Similar presentations


Presentation on theme: "Clinical Microbiology and Infection"— Presentation transcript:

1 Clinical Microbiology and Infection
New dosing strategies for liposomal amphotericin B in high-risk patients  Michael Ellis  Clinical Microbiology and Infection  Volume 14, Pages (May 2008) DOI: /j x Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

2 Fig. 1 (a) Amphotericin B concentration in lungs after one or four doses of LAB. (b) Fungal burden in lung tissue in mice infected with Aspergillus fumigatus treated for 3 days. Clinical Microbiology and Infection  , 55-64DOI: ( /j x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

3 Fig. 2 (a) Concentrations of amphotericin B in kidney of immunosuppressed mice. (b) Concentrations of amphotericin B in spleen of immunosuppressed mice. Clinical Microbiology and Infection  , 55-64DOI: ( /j x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

4 Fig. 3 (a) Amphotericin B concentration in spleen. (b) Log10 CFU/g kidney at 6 weeks post-treatment. Clinical Microbiology and Infection  , 55-64DOI: ( /j x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

5 Fig. 4 Fungal burden in kidney.
Clinical Microbiology and Infection  , 55-64DOI: ( /j x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

6 Fig. 5 High β-D-glucan levels in a patient without invasive fungal infection. Clinical Microbiology and Infection  , 55-64DOI: ( /j x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

7 Fig. 6 Bone marrow concentrations of amphotercin B.
Clinical Microbiology and Infection  , 55-64DOI: ( /j x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions


Download ppt "Clinical Microbiology and Infection"

Similar presentations


Ads by Google