1. Novel Epigenetic Markers on Chromosome 21 for Noninvasive Prenatal Testing of Fetal Trisomy 21 
Da Eun Lee, Ji Hyae Lim, Min Hyoung Kim, So Yeon Park, Hyun Mee Ryu 
The Journal of Molecular Diagnostics 
Volume 18, Issue 3, Pages (May 2016)
DOI: /j.jmoldx
Copyright © 2016 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

2. Figure 1
Heat map of samples, by study group. A high relative read frequency (log2 transformed) is indicated by the bright red shades, and low frequencies are shown in black. E, euploid fetus; N, nonpregnant women; P, pregnant women; T, trisomy 21 fetus.
The Journal of Molecular Diagnostics  , DOI: ( /j.jmoldx )
Copyright © 2016 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

3. Figure 2
D values of cases, by fetal karyotype. The line represents the optimal cutoff value of D for the noninvasive detection of fetal trisomy 21.
The Journal of Molecular Diagnostics  , DOI: ( /j.jmoldx )
Copyright © 2016 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

4. Figure 3
Receiver operating characteristics (ROC) curve of D values in the noninvasive detection of fetal trisomy 21. The overall accuracy of the D values was estimated according to the area under the ROC curve (AUC).
The Journal of Molecular Diagnostics  , DOI: ( /j.jmoldx )
Copyright © 2016 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions