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Propionibacterium acnes Strains Differentially Regulate the Fate of Th17 Responses in the Skin
Emmanuel Contassot, Lars E. French Journal of Investigative Dermatology Volume 138, Issue 2, Pages (February 2018) DOI: /j.jid Copyright © 2017 The Authors Terms and Conditions
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Figure 1 Propionibacterium acnes (P. acnes) strains induce different Th17 responses. Pathogenic (red arrows) and nonpathogenic (green arrows) P. acnes strains induce different cytokine release from cells composing or in close proximity of the pilosebaceous unit and induce the differentiation of IL-17A+/IFN-γ+ or IL-17A+/IL-10+ Th17 cells exhibiting pathogenic or protective properties, respectively. TGFβ, transforming growth factor-β; Th1, T helper type 1; Th17, T helper type 17; TNF, tumor necrosis factor. Journal of Investigative Dermatology , DOI: ( /j.jid ) Copyright © 2017 The Authors Terms and Conditions
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