1. Nose, olfactory region and the sinuses (L1) 2012

2. Nose
Olfactory mucosa
Respiratory mucosa
nasal conchae
Nose wings

3. Nasal ala lamina propria hyaline cartilage mixed glands hair
skeletal muscle
unkertinized stratified epithelium
Skin -OUTSIDE

4. Respiratory mucosa of nasal cavity
Ciliated pseudostratified
cylindrical epithelium
Mucous
goblet cells
artery
mixed glands
large veins
bone

5. Olfactory region Located in respiratory part of the nasal cavity
Begins at the front of the anterior end of the superior concha and extends posterior for about 1 cm
Extends laterally from the roof over the largest part of the superior concha and medially for about 1 cm over the nasal septum

6. Olfactory mucosa OLFACTORY EPITHELIUM LAMINA PROPRIA
Olfactory nerve fibers
Large veins
Gland of Bowman
LAMINA PROPRIA
bone

7. Olfactory epithelium Cell types
Pseudostratified cylindrical epithelium
Olfactory cells
Support cells
Basal cells
Olfactory cilia
Olfactory vesicle
dendrite
Support cell
Olfactory cell body
Basal cell
axon

8. Structure and function
Cell type
Structure and function
Pseudostratified
cylindrical epithelium
Ciliated (about 300 cilia on apical surface)
Mucus transport
Olfactory cells
Bipolar neurons, at apex 6-8 cilia
Very long non motile
Smell, generates action potential transmits impulse
Support cells
Broad cilindrical apexs with narrow bases
Microvilli are submerge in fluid layer
Well developed junctional complexes
Basal cells
Small, lie on basal lamina
Do not extend to surface
Generative stem cells

9. Lamina propria
Contains many veins - usually flat (Allergies - veins fill with blood and cause a blocked nose)
Contains tubulo-alveolar glands namely Bowman’s glands that secrete a thin watery substance that facilitates smell stimuli
Rest of the lamina propria contains mixed glands
The lamina propria is located against the perichondrium of the hyaline cartilage

10. Paranasal sinuses Mucosa Epithelium:
Pseudostratified cylindrical with cilia
Thinner than nasal epithelium
Less goblet cells and mixed glands
Thinner basement membrane
Lamina propria is thin and rests against the periosteum of the bone