1. No homework this week  Enjoy your holiday!
What are some possible ways to treat genetic disorders? Come up with 2 ideas.
No homework this week  Enjoy your holiday!

2. Example of a genetic disorder
Sickle cell anemia is a disorder that affects the shape and function of red blood cells
It is a recessive diseases, so to have the disease you must inherit TWO copies of the allele (one from each parent)
Those ‘diseased’ alleles are present in every cell in your body

3. Challenges of Treatment
What are some challenges to treating a genetic disorder?
Why is treating bacteria and viruses easier?

4. The future of genetic treatments!
CRISPR-Cas9

5. How did we discover this?
It is a part of the immune system in bacteria
Bacteria can ‘save’ the DNA of a virus so it can destroy it the next time it infects
This DNA sequence is specific and the CRISPR complex will ONLY kill that DNA

6. How can humans use this? Scientists can target specific DNA sequences
For example, they can target the damaged DNA in a sickle cell patient, cut that damaged DNA out, and replace it with healthy DNA

7. Is it safe? What’s happening now?

8. Is genetic engineering safe, helpful, and ethical?
engineered-salmon-too-fishy
genetic-modification.html
modified-mosquitoes-eliminate-dengue-fever
genetically-engineered-mosquitoes.html

9. Is genetic engineering safe, helpful, and ethical?
Each group will have 10 minutes to prepare their statements
You will give a 2 minute opening summary statement that summarizes your position (pro or con, why?)
We will then debate for 10 minutes
Be scientific in your statements- use evidence!