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Radiographic features of hand osteoarthritis in adult Kashin-Beck Disease (KBD): the Yongshou KBD study  Q. Fu, J. Cao, J.B. Renner, J.M. Jordan, B. Caterson,

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Presentation on theme: "Radiographic features of hand osteoarthritis in adult Kashin-Beck Disease (KBD): the Yongshou KBD study  Q. Fu, J. Cao, J.B. Renner, J.M. Jordan, B. Caterson,"— Presentation transcript:

1 Radiographic features of hand osteoarthritis in adult Kashin-Beck Disease (KBD): the Yongshou KBD study  Q. Fu, J. Cao, J.B. Renner, J.M. Jordan, B. Caterson, V. Duance, M. Luo, V.B. Kraus  Osteoarthritis and Cartilage  Volume 23, Issue 6, Pages (June 2015) DOI: /j.joca Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Hand radiographic features of KBD and the four criteria used for diagnosing adult KBD. Right hand of a 55 year old female KBD study participant with brachydactyly (A) and her right hand radiograph (B). The four hand radiographic features used for diagnosing adult KBD are marked with colored arrows: articular surface depression with sclerosis (yellow); “carpal crowding” (red); subchondral bone deformity in the proximal end of the phalanx (blue); and bony enlargement (between white arrows) with deformity of the distal end of phalanx (green). Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 Frequency of radiographic OA features of the joints of digit 1 (thumb) of the hand. The left panels represent the frequency of OST ≥ 1 (A), JSN ≥ 1 (B) and KL grade ≥ 2 (C) in the three joints of digit 1 (thumb). The right panels represent the severely affected subgroups with OST = 3 (D), JSN = 3 (E) and KL grade = 4 (F). IP, Interphalangeal joint; MCP, metacarpal-phalangeal joint; CMC, carpometacapal joint; All statistical analyses were adjusted for gender, age and BMI. +, P value < 0.05; ++, P value < 0.01; +++, P value < 0.001. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

4 Fig. 3 Frequency of radiographic features of the joints of digits 2–5 of the hand. The left panels represent the frequency of any OST ≥ 1 (A), any JSN ≥ 1 (B) and any KL grade ≥ 2 (C) in three joint groups: DIPs, PIPs and MCPs of the four fingers (digits 2–5). The right panels represent the severely affected subgroups with any OST = 3 (D), any JSN = 3 (E) and any KL grade = 4 (F). DIPs, distal interphalangeal joints; PIPs, proximal interphalangeal joints; MCPs, metacarpal-phalangeal joints. All statistical analyses were adjusted for gender, age and BMI. +, P value < 0.05; ++, P value < 0.01; +++, P value < 0.001. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions

5 Supplementary Fig. 1 Frequency of radiographic features of individual joints of digits 2–5 of the hand. The left panels represent the frequency of any OST ≥ 1 (A), any JSN ≥ 1 (B) and any KL grade ≥ 2 (C) in individual joints of the four fingers (digits 2–5). The right panels represent the severely affected subgroups with OST = 3 (D), JSN = 3 (E) and KL grade = 4 (F). DIP, distal interphalangeal joint; PIP, proximal interphalangeal joint; MCP, metacarpal-phalangeal joint; D2, D3, D4 and D5 refers to digits 2 through 5. All statistical analyses were adjusted for gender, age and body mass index (BMI). +, P value < 0.05; ++, P value < 0.01; +++, P value < 0.001. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2015 Osteoarthritis Research Society International Terms and Conditions


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