1. Oleuropein or rutin consumption decreases the spontaneous development of osteoarthritis in the Hartley guinea pig 
M.-N. Horcajada, C. Sanchez, F. Membrez Scalfo, P. Drion, F. Comblain, S. Taralla, A.-F. Donneau, E.A. Offord, Y. Henrotin 
Osteoarthritis and Cartilage 
Volume 23, Issue 1, Pages (January 2015)
DOI: /j.joca
Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

2. Fig. 1
Representative pictures of medial compartment of right guinea pig knees of each group, at week 35. Control = control group, Oleur = Oleuropein group, Rut = Rutin group, Rut + Cur = Rutin + curcumin group. Safranin-O/fast green/hematoxylin staining, 5× magnification.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

3. Fig. 2
(A) Global OA score. (B) Cartilage surface integrity score. (C) Proteoglycans content score. (D) Cellularity score. (E) Tidemark integrity score. (F) Osteophyte score. Mean ± 95% CI, * = P < 0.05, ** = P < 0.01, *** = P < 0.001, one-way ANOVA with Dunnet's post-test.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

4. Fig. 3
(A) Global synovial histological score in each group. (B): PGE2 levels found in guinea pig sera at week 4 or week 35. Mean ± 95% CI, * = P < 0.05, ** = P < 0.01 and *** = P < 0.001, one-way ANOVA with Dunnet's post-test.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

5. Fig. 4
(A) Coll2-1 (B) Coll2-1NO2 (C) Fib3-1 (D) Fib3-2 levels found in guinea pig sera. Means ± 95% CI.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions

6. Fig. 5
ARGS levels found in guinea pig sera. (A) across time (B) at week 35. Means ± 95% CI, * = P < 0.05 one-way ANOVA with Dunnet's post-test.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2014 Osteoarthritis Research Society International Terms and Conditions