Presentation is loading. Please wait.

Presentation is loading. Please wait.

Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonography  Chiara Barisione, BSc,

Published byOscar Mason Modified over 6 years ago

Similar presentations

Presentation on theme: "Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonography  Chiara Barisione, BSc,"— Presentation transcript:

1 Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonography  Chiara Barisione, BSc, Richard Charnigo, PhD, Deborah A. Howatt, BSc, Jessica J. Moorleghen, BSc, Debra L. Rateri, BSc, Alan Daugherty, PhD, DSc  Journal of Vascular Surgery  Volume 44, Issue 2, Pages (August 2006) DOI: /j.jvs Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

2 Fig 1 Measurement of murine aortic luminal dimensions in vivo by ultrasonography. Photographs are shown of apolipoprotein E−/− mice infused with either saline (left) or angiotensin II (right) for 28 days. The regions used to acquire images are indicated on these photographs. Samples of short-axis ultrasonic images at these abdominal aortic regions are shown (A and C, suprarenal region; B and D, at the level the left renal branch). The perimeter of the aortic lumen is outlined by yellow dotted lines. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

3 Fig 2 Comparison of aortic lumen measurements acquired in vivo by ultrasonography and ex vivo by histology. Apolipoprotein E−/− mice infused with either saline or angiotensin II for 28 days were subjected to ultrasonography to determine the maximum lumen diameter in the suprarenal region. At the termination of the study, mice were perfusion-fixed at approximately 100 mm Hg, and their entire suprarenal aortas were sectioned to determine the region of maximal dilation. Points represent the maximal lumen diameter for individual mice for ex vivo and in vivo measurements. The two measurements were highly correlated with each other (r = ). Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

4 Fig 3 Sequential measurements of abdominal aortic luminal diameters of apolipoprotein E−/− mice during infusion with either saline or angiotensin II (AngII). Mice were infused with saline or AngII for 28 days and monitored at frequent intervals. Data are shown for AngII-infused mice that developed abdominal aortic aneurysms and survived the infusion period. Abdominal aortic luminal diameters were measured in the suprarenal region of mice infused with saline (triangles; n = 8 at all time points) or AngII (circles; n = 12). Data are based on the measurement of diameters at each time point by at least two independent operators. Symbols represent means, and bars represent SEMs. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

5 Fig 4 Lumen diameters of the suprarenal aortas of angiotensin II–infused mice that subsequently died of abdominal aortic rupture. Each curve represents an example of temporal changes in luminal diameters of individual mice. In all of these examples, aortic rupture of the suprarenal region occurred 1 or 2 days after the final luminal measurement. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Download ppt "Rapid dilation of the abdominal aorta during infusion of angiotensin II detected by noninvasive high-frequency ultrasonography  Chiara Barisione, BSc,"

Similar presentations

Large renal artery aneurysm in Takayasu arteritis

Large renal artery aneurysm in Takayasu arteritis
Delayed migration of a thrombosed aortic endograft within a thrombosed aneurysm sac resulting in continued sac expansion and rupture  Edvard Skripochnik,

Delayed migration of a thrombosed aortic endograft within a thrombosed aneurysm sac resulting in continued sac expansion and rupture  Edvard Skripochnik,
Mesenchymal stem cells attenuate angiotensin II-induced aortic aneurysm growth in apolipoprotein E-deficient mice  Ryotaro Hashizume, MD, Aika Yamawaki-Ogata,

Mesenchymal stem cells attenuate angiotensin II-induced aortic aneurysm growth in apolipoprotein E-deficient mice  Ryotaro Hashizume, MD, Aika Yamawaki-Ogata,
Ultrasound-determined diameter measurements are more accurate than axial computed tomography after endovascular aortic aneurysm repair  Sukgu M. Han,

Ultrasound-determined diameter measurements are more accurate than axial computed tomography after endovascular aortic aneurysm repair  Sukgu M. Han,
Accelerated aneurysmal dilation associated with apoptosis and inflammation in a newly developed calcium phosphate rodent abdominal aortic aneurysm model 

Accelerated aneurysmal dilation associated with apoptosis and inflammation in a newly developed calcium phosphate rodent abdominal aortic aneurysm model 
Castration of male mice prevents the progression of established angiotensin II-induced abdominal aortic aneurysms  Xuan Zhang, PhD, Sean Thatcher, PhD,

Castration of male mice prevents the progression of established angiotensin II-induced abdominal aortic aneurysms  Xuan Zhang, PhD, Sean Thatcher, PhD,
Meryl Davis, FRCS, Mike Harris, BSc (Hons), Jonothan J

Meryl Davis, FRCS, Mike Harris, BSc (Hons), Jonothan J
Hyperglycemia limits experimental aortic aneurysm progression

Hyperglycemia limits experimental aortic aneurysm progression
Mark J.W. Koelemay, MD, PhD  Journal of Vascular Surgery 

Mark J.W. Koelemay, MD, PhD  Journal of Vascular Surgery 
Richard T. Purdy, M. D. , Frederick C. Beyer, M. D. , William D

Richard T. Purdy, M. D. , Frederick C. Beyer, M. D. , William D
Nicholas B. Cavanaugh, BS, Lan Qian, MD, Nicole M

Nicholas B. Cavanaugh, BS, Lan Qian, MD, Nicole M
Retrograde migration of an abdominal aortic aneurysm endograft leading to postoperative renal failure  Barry T. Katzen, MD, Alexandra A. MacLean, MD,

Retrograde migration of an abdominal aortic aneurysm endograft leading to postoperative renal failure  Barry T. Katzen, MD, Alexandra A. MacLean, MD,
Loss of STAT1 is associated with increased aortic rupture in an experimental model of aortic dissection and aneurysm formation  Matthew J. Eagleton, MD,

Loss of STAT1 is associated with increased aortic rupture in an experimental model of aortic dissection and aneurysm formation  Matthew J. Eagleton, MD,
Delayed migration of a thrombosed aortic endograft within a thrombosed aneurysm sac resulting in continued sac expansion and rupture  Edvard Skripochnik,

Delayed migration of a thrombosed aortic endograft within a thrombosed aneurysm sac resulting in continued sac expansion and rupture  Edvard Skripochnik,
Ex vivo renal artery reconstruction for complex renal artery disease

Ex vivo renal artery reconstruction for complex renal artery disease
Suppression of experimental abdominal aortic aneurysms in mice by treatment with pyrrolidine dithiocarbamate, an antioxidant inhibitor of nuclear factor-κB 

Suppression of experimental abdominal aortic aneurysms in mice by treatment with pyrrolidine dithiocarbamate, an antioxidant inhibitor of nuclear factor-κB 
Amir H. Malkawi, MRCS, Robert J

Amir H. Malkawi, MRCS, Robert J
Renal perfusion with venous blood extends the permissible suprarenal clamp time in abdominal aortic surgery  Maximilian Pichlmaier, MA, MD, Ludwig Hoy,

Renal perfusion with venous blood extends the permissible suprarenal clamp time in abdominal aortic surgery  Maximilian Pichlmaier, MA, MD, Ludwig Hoy,
PC222. Loss of Normal Fiber Orientation in Human Abdominal Aortic Aneurysmal Tissue and Increased Energy Loss  Sandra Toth, BS, Doran Mix, MD, BS, Ibrahima.

PC222. Loss of Normal Fiber Orientation in Human Abdominal Aortic Aneurysmal Tissue and Increased Energy Loss  Sandra Toth, BS, Doran Mix, MD, BS, Ibrahima.
Reference value of transcutaneous oxygen measurement in diabetic patients compared with nondiabetic patients  Vincent E. de Meijer, MD, MSc, Hans P. van't.

Reference value of transcutaneous oxygen measurement in diabetic patients compared with nondiabetic patients  Vincent E. de Meijer, MD, MSc, Hans P. van't.

Similar presentations

Ads by Google