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Exome Sequencing Followed by Large-Scale Genotyping Suggests a Limited Role for Moderately Rare Risk Factors of Strong Effect in Schizophrenia  Anna C.

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Presentation on theme: "Exome Sequencing Followed by Large-Scale Genotyping Suggests a Limited Role for Moderately Rare Risk Factors of Strong Effect in Schizophrenia  Anna C."— Presentation transcript:

1 Exome Sequencing Followed by Large-Scale Genotyping Suggests a Limited Role for Moderately Rare Risk Factors of Strong Effect in Schizophrenia  Anna C. Need, Joseph P. McEvoy, Massimo Gennarelli, Erin L. Heinzen, Dongliang Ge, Jessica M. Maia, Kevin V. Shianna, Min He, Elizabeth T. Cirulli, Curtis E. Gumbs, Qian Zhao, C. Ryan Campbell, Linda Hong, Peter Rosenquist, Anu Putkonen, Tero Hallikainen, Eila Repo-Tiihonen, Jari Tiihonen, Deborah L. Levy, Herbert Y. Meltzer, David B. Goldstein  The American Journal of Human Genetics  Volume 91, Issue 2, Pages (August 2012) DOI: /j.ajhg Copyright © 2012 The American Society of Human Genetics Terms and Conditions

2 Figure 1 Range of Relative Risks and MAFs that Are Detectable with 99% Power at p < 0.05 and, after Correction for All Included Variants, p < 1.5 × 10−7 in a Cohort of 166 Cases and 307 Controls The American Journal of Human Genetics  , DOI: ( /j.ajhg ) Copyright © 2012 The American Society of Human Genetics Terms and Conditions

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