1. The Great Divide 1 Mitosis: 05/04 Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
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May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today
05/04 1

2. To Be Answered… THINK: How many cells are you composed of?
When an organism grows bigger do you get more cells or just bigger cells or both?
When do your cells divide the fastest? Slowest?
Do cells ever stop dividing?
Are all cells capable of division and replacement?
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 2

3. Why Would a Cell Divide? Solution: divide in 2!
As cells absorb nutrients and get larger, the volume of the cell increases faster than the surface area
This means that a cell can no longer absorb nutrients and get rid of wastes fast enough to support its demands (volume)
So what’s a cell to do?
Solution: divide in 2!
Surface area for exchange not great enough to support cell’s needs
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 3

4. When Would a Cell Divide?
Growth
Repair or Replacement
Cancer
Different cells divide at different rates:
Most mammalian cells = hours
Some bacterial cells = minutes
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 4

5. Getting Older… How does cell division change over a lifetime?
All cells are only allowed to complete a certain number of divisions
Then they die (programmed cell death)
How does cell division change over a lifetime?
Childhood = cell division > cell death
Adulthood = cell division = cell death
The Later Years = cell division < cell death
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 5

6. The Cell Cycle 6 Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 6

7. Stages of the Cell Cycle
Cell division occurs in a series of stages or phases.
Cell spends about 90% of the time in interphase
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 7

8. 1st Interphase Divided into 3 phases:
G1 (1st gap) = small cell is absorbing nutrients, growing & doing its job (i.e. making proteins)
S (synthesis) = cell is continuing to grow & Chromosomes are copied (# doubles). Chromosomes appear as threadlike coils (chromatin ) at the start, but each chromosome and its copy (sister chromosome) change to sister chromatids at the end of this phase.
G2 (2nd gap) = cell keeps growing & doing its job (i.e. making proteins); it grows too big…solution = divide in 2
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 8

9. Warm -up 3/5/18
The two main stages of cell division are ________________ and _________________.
2. Which pair of terms is correct?
a. S phase, cell division b. G1 phase, DNA replication
c. M phase, cell growth d. G2 phase, preparation for mitosis
3. Put the phases of mitosis is order.
4. The purpose of mitosis is to produce _______ genetically ________________ cells.

10. Mitosis: A Closer Look Interphase
Prior to entering the mitotic phase, the cell has just come out of interphase
Replicated DNA during S (synthesis)
2 complete sets of chromosomes that must be distributed equally between 2 cells = mitosis
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 10

11. The Mitotic Phase
Equal distribution of 2 sets of chromosomes (DNA) into 2 identical daughter cells
Divided into 4 stages of Mitosis:
Prophase
Metaphase
Anaphase
Telophase
Cytokinesis
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 11

12. Cell Cycle Tidbits How long is one cell cycle?
Depends on the cell- skin cells = ~24 hours, nerve cells = never after maturity, cancer cells = very short
Remember: every cell only has a certain # of divisions it can undergo, then it dies = apoptosis (programmed cell death)
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 12

13. 2nd Prophase Mitosis begins (cell begins to divide)
Centrioles ( or poles ) appear and begin to move to the opposite ends of the cell.
Spindle fibers form between the poles.
Thanks to person who introduced me
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Different, wacky, interactive
Reason for madness- will be reviewed during implications
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May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 13

14. 3rd Metaphase
Chromatids or pairs of chromosomes line-up in the middle.
Centromeres are attached to spindle fibers
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 14

15. 4th Anaphase
Chromatids (chromosome pairs) separate and begin to move to opposite ends of the cell.
Thanks to person who introduced me
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Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 15

16. 5th Telophase Two new nuclei form.
Chromosomes appear as chromatin(threads rather than rods) *Mitosis ends.
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 16

17. Cytokinesis
Cell membrane moves inward to create two daughter cells- each with its own nucleus with identical chromosomes.
Animal
Plant
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 17

18. What Mitosis Actually Looks Like
Interphase
Metaphase
Prophase
Thanks to person who introduced me
Explain presentation style
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Reason for madness- will be reviewed during implications
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May be asked to reinforce others
Will be reinforced with candy
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Reinforce me for doing well
Have participants guess the number of new things they will learn today
Telophase
Anaphase 18

19. Summary of Mitosis 19 Thanks to person who introduced me
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Reason for madness- will be reviewed during implications
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May be asked to reinforce others
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Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 19

20. What Happens After Mitosis?
The cell returns to interphase
Chromosomes uncoil back into chromatin
The cycle repeats itself over & over…
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 20

21. At What Stage Are Our Cells At In The Cell Cycle?
Different cells can be in different stages
Interphase
Mitosis:
Prophase
Metaphase
Anaphase
Telophase
Cytokinesis
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 21

22. Can You Identify the Stages of Mitosis?
Put the following mitosis stages in the correct sequence
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today 22

23. Identical daughter cells
The Guarantee
The product of mitosis is 2 cells
The daughter cells are identical to each other & to the mother cell
Mother cell
Identical daughter cells
Why is this so important?

24. Identical daughter cells
The Daughter Cells
In humans, the 2 daughter cells will have 46 chromosomes (23 pairs)
1 chromosome originally from mom & 1 from dad
Each chromosome is said to have the same gene sequence
Identical daughter cells

25. Warm -up 3/6/18, copy the following into your notebook
Diploid
Haploid
Diploid= 2(n)
In humans
n= 23 chromosomes
2(n)= 46 total chromosomes
2 sets of each chromosomes
Somatic cells are diploid
Body cells (nerve, muscle, bone, etc)
Haploid= n
In humans
n= 23 chromosomes
Only 23 total chromosomes
1 set of each chromosomes
Gamete cells are haploid
Sex Cells (Sperm & Egg)

26. Karyotypes
Karyotypes: a organized profile of a person's chromosomes. Two chromosomes specify sex (23rd pair), XX for female and XY for male. The rest are rearranged in pairs numbered 1- 22, from largest to smallest. These are known as autosomes.
This arrangement is used to quickly identify abnormalities (too many chromosomes, missing chromosomes, normal).

27. Normal Female

28. Normal Male

29. Abnormal??

30. Identical daughter cells
The Beauty of Asexual Reproduction
Mitosis is a form of asexual reproduction
New individuals are produced by 1 parent & thus, are identical to their parent
Mother cell
Runners produces by strawberries
Thanks to person who introduced me
Explain presentation style
Different, wacky, interactive
Reason for madness- will be reviewed during implications
May be asked to be an active participant
May be asked to reinforce others
Will be reinforced with candy
Comments/questions welcomed throughout
Reinforce me for doing well
Have participants guess the number of new things they will learn today
Identical daughter cells
Budding by hydra & yeast
Cuttings from plants 30