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Published byIrma Gaines Modified over 6 years ago
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Bariatric Surgery Restores Gut-Brain Signaling to Reduce Fat Intake
Stephanie Caligiuri, Paul J. Kenny Cell Metabolism Volume 25, Issue 2, Pages (February 2017) DOI: /j.cmet Copyright © 2017 Elsevier Inc. Terms and Conditions
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Figure 1 Gastric Bypass in Rats Restores Gut-Brain Signaling
Left panel: obese animals show desensitized intestinal production of the OEA, which serves as a satiety signal for dietary lipids, blunted striatal dopamine responses to high-fat food, and increased preference for high-fat food. Right panel: Roux-en-Y gastric bypass surgery in rats restores intestinal OEA production in response to dietary lipids, dramatically enhances striatal dopamine transmission in response to high-fat food, and reduces preference for high-fat food. Cell Metabolism , DOI: ( /j.cmet ) Copyright © 2017 Elsevier Inc. Terms and Conditions
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