1. Lesson starter Explain how phagocytes work
Why do we rarely get infected with the same infection twice?

2. Cells Alive
Fighting back!

3. Today we are going to.. Learn about transplants
Learn about vaccinations

4. Think.. Pair.. Share What is it ?
If your immune system can tell the difference between what is yours and not yours then this can cause a problem.
What is it ?

5. Transplanted Organs
A transplanted organ does not belong to you and your immune system can attack and destroy the organ called rejection

6. Organ Transplants The waiting list..
You go onto the transplant waiting list while doctors try to find an organ that is a good match for you.
Although organs from different people work in the same way, there are some differences between them
They are differences in the antigens on the outside of cells.
If antigens on donor organ are different from your own then your body will attack the new organ (and treat it as an invader)

7. Size matters!
The size and age of the donor is also important in matching. For example, a big heart wouldn't fit into a small body, and a small heart wouldn't pump enough blood for a big body!

8. What happens next?
Once an organ has been removed from a donor, is has to be transplanted quickly so that it will still work. If the donor isn't in the same hospital as you, it will be sped to you by motorbike, car, helicopter or even aeroplane! 

9. What happens next?
Under general anaesthetic, the surgeon will go inside and disconnect all the plumbing and blood vessels from the old organ. 
The new organ will be inserted once the old organ has been removed, and all the pipes and blood vessels will be reconnected

10. Stopping rejection
Unless the donor is your twin, finding an exact match is very unlikely
This means that your new organ will still have some foreign antigens, so your immune system might still attack it. This is called transplant rejection. To stop this from happening, the doctor will give medicines called IMMUNOSUPPRESSENTS

11. Why may this be a problem?
Immunosuppressants
A drug which lowers the efficiency of the immune system
Why may this be a problem?

12. Vaccination
Vaccines are a way of making the body produce antibodies without the risk of catching the disease.
You are injected with a harmless version of a microbe but your body still makes antibodies.

13. Vaccination
If a harmful version of the microbe does invade your body you will already have antibodies to kill it and wont get sick.
Common vaccines used today are the MMR (measles, mumps and rubella) and polio

14. The discovery of vaccination
Watch the video and take notes in your jotter about the discovery of vaccines

15. Vaccination Who developed vaccines?
What type of virus was the first vaccine for?
What type of people were immune to the virus?
How was this information used?

16. Write a summary about the discovery of vaccines