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In vitro hemodynamic model of the arm arteriovenous circulation to study hemodynamics of native arteriovenous fistula and the distal revascularization.

Published byBartholomew Johnston Modified over 5 years ago

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Presentation on theme: "In vitro hemodynamic model of the arm arteriovenous circulation to study hemodynamics of native arteriovenous fistula and the distal revascularization."— Presentation transcript:

1 In vitro hemodynamic model of the arm arteriovenous circulation to study hemodynamics of native arteriovenous fistula and the distal revascularization and interval ligation procedure  Nicole Varble, MS, Steven Day, PhD, Daniel Phillips, PhD, Doran Mix, BS, Karl Schwarz, MD, Karl A. Illig, MD, Ankur Chandra, MD  Journal of Vascular Surgery  Volume 59, Issue 5, Pages (May 2014) DOI: /j.jvs Copyright © 2014 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Noncompliant tubing, capable of acquiring pressure measurements at each junction through pressure transducers (bottom arrow) and flow through each segment of tubing through flow probes (top arrow). Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Schematic of Hemodynamic Simulator Pump (image credited to Matthew DeCapua; published with permission). Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

4 Fig 3 Configuration of the final experimental setup. The distal revascularization and interval ligation (DRIL) bypass and IL (dashed line) are shown with the black arrows indicating the direction of flow. The elimination of the DRIL bypass and the IL would result in the arteriovenous fistula (AVF) configuration. The AVF is a bridge between the arterial and venous circulation. The native circulation would result in the elimination of the DRIL and AVF from the picture shown. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

5 Fig 4 Comparison of the changing hemodynamics under the test configurations of the native circulation (NC), arteriovenous fistula (AVF), distal revascularization without interval ligation (DR no IL), and full distal revascularization and interval ligation (DRIL) procedure. dP represents the change in distal pressure between the arterial and venous sides. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

6 Fig 5 Physiologic pressure waveforms from in vitro arterial and venous circulation. The top line represents the arterial pressure (pulse pressure of 65 mm Hg) at the subclavian-aorta bifurcation. The dashed line represents the distal venous pressure. The waveforms were generated by the hemodynamic simulator. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2014 Society for Vascular Surgery Terms and Conditions

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