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Human versus mouse eosinophils: “That which we call an eosinophil, by any other name would stain as red”  James J. Lee, PhD, Elizabeth A. Jacobsen, PhD,

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Presentation on theme: "Human versus mouse eosinophils: “That which we call an eosinophil, by any other name would stain as red”  James J. Lee, PhD, Elizabeth A. Jacobsen, PhD,"— Presentation transcript:

1 Human versus mouse eosinophils: “That which we call an eosinophil, by any other name would stain as red”  James J. Lee, PhD, Elizabeth A. Jacobsen, PhD, Sergei I. Ochkur, PhD, Michael P. McGarry, PhD, Rachel M. Condjella, PhD, Alfred D. Doyle, BS, Huijun Luo, PhD, Katie R. Zellner, BS, Cheryl A. Protheroe, BA, Lian Willetts, BS, William E. LeSuer, BS, Dana C. Colbert, MS, Richard A. Helmers, MD, Paige Lacy, PhD, Redwan Moqbel, PhD, FRCPath, Nancy A. Lee, PhD  Journal of Allergy and Clinical Immunology  Volume 130, Issue 3, Pages (September 2012) DOI: /j.jaci Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Hematopoietic differentiation pathways leading to eosinophils in human subjects versus mice. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Human versus mouse eosinophils stained with Romanowsky dye sets reveal remarkable similarities in cell morphology punctuated by subtle differences, the significance of which is not yet fully understood. Representative eosinophils were identified from stained blood films of a human subject and a BALB/CJ mouse and shown in comparison. Scale bars = 5 μm. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions


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