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TNM classification system for primary cutaneous lymphomas other than mycosis fungoides and Sézary syndrome: a proposal of the International Society for.

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Presentation on theme: "TNM classification system for primary cutaneous lymphomas other than mycosis fungoides and Sézary syndrome: a proposal of the International Society for."— Presentation transcript:

1 TNM classification system for primary cutaneous lymphomas other than mycosis fungoides and Sézary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the Cutaneous Lymphoma Task Force of the European Organization of Research and Treatment of Cancer (EORTC)‏ by Youn H. Kim, Rein Willemze, Nicola Pimpinelli, Sean Whittaker, Elise A. Olsen, Annamari Ranki, Reinhard Dummer, and Richard T. Hoppe Blood Volume 110(2): July 15, 2007 ©2007 by American Society of Hematology

2 Body regions as defined in the proposed TNM system for the designation of T (skin involvement) category. Body regions as defined in the proposed TNM system for the designation of T (skin involvement) category. Left and right extremities are assessed as separate body regions. The designation of these body regions are based on regional LN drainage patterns. Youn H. Kim et al. Blood 2007;110: ©2007 by American Society of Hematology

3 Clinical examples of proposed T1 (discrete solitary lesion) category of primary cutaneous lymphomas.
Clinical examples of proposed T1 (discrete solitary lesion) category of primary cutaneous lymphomas. (A) T1a (solitary lesion equal or less than 5 cm), CD30 + anaplastic large cell lymphoma. (B) T1b (solitary lesion greater than 5 cm), NK/T-cell, nasal-type, lymphoma. Youn H. Kim et al. Blood 2007;110: ©2007 by American Society of Hematology

4 Clinical examples of proposed T2a (regional involvement with lesions within a 15 cm diameter area) category of primary cutaneous lymphomas. Clinical examples of proposed T2a (regional involvement with lesions within a 15 cm diameter area) category of primary cutaneous lymphomas. (A) CD30 + anaplastic large cell lymphoma. (B) Follicle center lymphoma. (C) Diffuse large B-cell lymphoma, leg-type. Youn H. Kim et al. Blood 2007;110: ©2007 by American Society of Hematology

5 Clinical examples of proposed T2b (regional involvement with lesions in an area between 15 cm and 30 cm diameter) category of primary cutaneous lymphomas. Clinical examples of proposed T2b (regional involvement with lesions in an area between 15 cm and 30 cm diameter) category of primary cutaneous lymphomas. (A) diffuse large B-cell lymphoma, leg-type. (B) Follicle center lymphoma. (C) Follicle center lymphoma. Youn H. Kim et al. Blood 2007;110: ©2007 by American Society of Hematology

6 Clinical examples of proposed T2c (regional involvement with lesions more than 30 cm in diameter) category of cutaneous lymphomas. Clinical examples of proposed T2c (regional involvement with lesions more than 30 cm in diameter) category of cutaneous lymphomas. (A) Diffuse large B-cell lymphoma, leg-type. (B) Follicle center lymphoma. (C) Diffuse large B-cell lymphoma, leg-type. Youn H. Kim et al. Blood 2007;110: ©2007 by American Society of Hematology

7 Clinical examples of proposed T3 (generalized) category of cutaneous lymphomas.
Clinical examples of proposed T3 (generalized) category of cutaneous lymphomas. (A) T3a (multiple lesions involving 2 noncontiguous body regions), follicle center lymphoma. (B) T3b (multiple lesions involving 3 or more body regions), CD30 + anaplastic large-cell lymphoma. Youn H. Kim et al. Blood 2007;110: ©2007 by American Society of Hematology

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