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Mild Cognitive Impairment and Mild Dementia: A Clinical Perspective

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1 Mild Cognitive Impairment and Mild Dementia: A Clinical Perspective
David S. Knopman, MD, Ronald C. Petersen, PhD, MD  Mayo Clinic Proceedings  Volume 89, Issue 10, Pages (October 2014) DOI: /j.mayocp Copyright © 2014 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure Graphic demonstration of the differences in cognitive trajectories between a person destined to never become cognitively impaired during life (blue line) and a person destined to have development of dementia (orange line). The x-axis represents age, and the y-axis represents cognitive impairment. Thresholds for mild cognitive impairment (MCI) and dementia are indicated by horizontal orange bands. The continuous nature of cognitive decline in persons destined to have dementia defies simple algorithms; clinical judgment is needed to weigh information from the history and examination. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2014 Mayo Foundation for Medical Education and Research Terms and Conditions


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