6. H

7. M

8. M IF

11. Causes of Pulmonary Hypertension in Patients with Sarcoid
Perivascular fibrosis
Increased vasoreactivity
Granulomas in pulmonary arteries and/or veins
Extrinsic compression from mediastinal adenopathy or fibrosis
Decreased NO synthesis or release
Pulmonary Venous Occlusive Disease (PVOD)
Endothelin?

12. Congested
capillary

13. VV

15. Pulmonary Veno-occlusive Disease
PVOD is a rare cause of mild/moderate pulmonary hypertension
Etiology is not always clear
Site of occlusion ranges from post-capillary to large pulmonary veins
May be associated with mediastinal or left atrial obstruction

16. Pathologic Diagnoses
Pulmonary Sarcoidosis diagnosed 2006 by lung biopsy
Clinical pulmonary hypertension diagnosed by right heart catheter study in 2007
Cor pulmonale and liver congestion
Diffuse alveolar Damage in lungs at autopsy
Pulmonary Veno-occlusive Disease