1. Punnett Square Notes

2. Gregor Mendel Father of Genetics 1st important studies of heredity
Identified specific traits in the garden pea and studied them from one generation to another

3. Mendel’s Conclusions
Law of Segregation – Two alleles for each trait separate when gametes form; Parents pass only one allele for each trait to each offspring
Law of Independent Assortment – Genes for different traits are inherited independently of each other

4. What is Genetics?
Genetics is the scientific study of heredity

5. What is a Trait?
A trait is a specific characteristic that varies from one individual to another.
Examples: Brown hair, blue eyes, tall, curly

6. What is an Allele?
Alleles are the different possibilities for a given trait.
Every trait has at least two alleles (one from the mother and one from the father)
Example: Eye color – Brown, blue, green, hazel
Examples of Alleles:
B = Brown Eyes
b = Blue Eyes
G = Green Eyes
g = Hazel Eyes

7. What are Genes?
Genes are the sequence of DNA that codes for a protein and thus determines a trait.

8. R r Dominant vs. Recessive
Dominant - Masks the other trait; the trait that shows if present
Represented by a capital letter
Recessive – An organism with a recessive allele for a particular trait will only exhibit that trait when the dominant allele is not present; Will only show if both alleles are present
Represented by a lower case letter R r

9. Incomplete Dominance
Incomplete Dominance - Situation in which one allele is not completely dominant over another.
Example – Red and white flowers are crossed and pink flowers are produced.

10. Codominance
Codominance - Situation in which both alleles of a gene contribute to the phenotype of the organism.
Example – A solid white cow is crossed with a solid brown cow and the resulting offspring are spotted brown and white (called roan). +

11. Dominant & Recessive Practice
Upper case letters represent Dominant traits.
Lower case letters represent Recessive traits.
TT - Represent offspring with straight hair
Tt - Represent offspring with straight hair
tt - Represents offspring with curly hair
T – straight hair
t - curly hair

12. Homozygous vs. Heterozygous
Homozygous – Term used to refer to an organism that has two identical alleles for a particular trait (TT or tt)
Heterozygous - Term used to refer to an organism that has two different alleles for the same trait (Tt) RR rr Rr

13. Genotype vs. Phenotype
Genotype – The genetic makeup of an organism; The gene (or allele) combination an organism has.
Example: Tt, ss, GG, Ww
Phenotype – The physical characteristics of an organism; The way an organism looks
Example: Curly hair, straight hair, blue eyes, tall, green

14. Punnett Squares
Punnett Square – Diagram showing the gene combinations that might result from a genetic cross
Used to calculate the probability of inheriting a particular trait
Probability – The chance that a given event will occur

16. Punnett Square
Parent
Offspring
Parent

17. How to Complete a Punnett Square

18. Y-Yellow
y-white
Genotype:
1:2:1
(YY:Yy:yy)
Phenotype:
3 Yellow
1 White

19. Let’s put a couple examples in our notebook!

20. You Try It Now! Complete the following punnett square problems in your SISN.
Create a punnett square and give the genotype and phenotype for the following cross: TT x tt (T = Tall and t = Short)

21. TT x tt
Step One: Set Up Punnett Square (put one parent on the top and the other along the side)
T T t

22. TT x tt
Step Two: Complete the Punnett Square
T T t Tt

23. TT x tt Tt t Genotype: 4 - Tt Phenotype: 100% Tall
Step Three: Write the genotype and phenotype
T T t
Genotype:
4 - Tt
Phenotype:
100% Tall Tt
Remember: Each box is 25%

24. You Try It . Complete the following punnett square problems in your SISN.
Give the genotype and phenotype for the following cross: Tt x tt

25. Tt x tt
Step One: Set Up Punnett Square (put one parent on the top and the other along the side)
T t
t t

26. Tt x tt
Step Two: Complete the Punnett Square
T t t Tt tt

27. Tt x tt Tt tt t Genotype: Tt - 2 (50%) tt - 2 (50%) Phenotype:
Step Two: Complete the Punnett Square
T t t
Genotype:
Tt - 2 (50%)
tt - 2 (50%)
Phenotype:
50% Tall
50% Short Tt tt
Remember: Each box is 25%

28. Work through the practice!!!

29. Punnett Square Pop Quiz
Take out a blank sheet of notebook paper and something to write with.

30. B – Brown eyes b – Blue Eyes
1. What is the dominant gene? What is the recessive gene?
B – Brown eyes
b – Blue Eyes

31. 2. Label which is heterozygous and which is homozygous.BB Bb bb

32. 3. A scientist crossed a homozygous tall daisy with a homozygous short daisy. Each of the daisies has two of the same alleles that make them homozygous. The tall trait of the daisy is the dominant, and is represented with a “D”. The short trait of the daisy is the recessive trait, and is represented with a “d”.
Use a Punnett Square to cross a homozygous tall daisy (DD) with a homozygous short daisy (dd).

33. 4. In the first question, what is the genotype and phenotype of all the 1st generation offspring?
Genotype ________________
Phenotype ________________

34. 5. Black fur (B) in guinea pigs is dominant over white fur (b)
5. Black fur (B) in guinea pigs is dominant over white fur (b). Create a punnett square that displays the offspring if a heterozygous black fur guinea pig is crossed with a homozygous white fur guinea pig.

35. Multiple Alleles
Multiple Alleles- Three or more alleles of the same gene.
Even though three or more alleles exist for a particular trait, an individual can only have two alleles - one from the mother and one from the father.

36. Examples of Multiple Alleles
Coat color in rabbits is determined by a single gene that has at least four different alleles. Different combinations of alleles result in the four colors you see here.

37. Examples of Multiple Alleles
Blood Type – 3 alleles exist (IA, IB, and io), which results in four different possible blood types
What are the four main blood types?
Hair Color – Too many alleles exist to count
There are over 20 different shades of hair color.

38. Blood type punnett squares

39. Blood Type Punnett Square
A man who is AB marries a woman who is heterozygous type B. If they had four children, what would their probable genotypes and phenotypes be?
*hint – you will need to create a punnett square.

41. Multiple Alleles There Are Always Multiple Alleles!
Genetic inheritance is often presented with straightforward examples involving only two alleles with clear-cut dominance. This makes inheritance patterns easy to see.
But very few traits actually only have two alleles with clear-cut dominance. As we learn more about genetics, we have found that there are often hundreds of alleles for any particular gene.
We probably know this already - as we look around at other people, we see infinite variation.

42. Blood type