1. Mitosis

2. = division of the nucleus and its contents
Mitosis
= division of the nucleus and its contents
- discovered by Walther Flemming in 1882

3. Phases of Mitosis

4. 1) Prophase - DNA coils to become chromosomes
- nuclear membrane disappears
- microtubules called spindle fibers grow from centrioles to center of cell

5. Prophase
Centrioles
Nucleus with Chromosomes
Spindle Fibers

6. Late Prophase
Kinetochore Fibers
Polar Fibers

7. 2) Metaphase
- chromosomes line up in center

8. Metaphase

9. 3) Anaphase
- chromosomes pull apart and move to opposite sides of cell

10. Anaphase

11. 4) Telophase
- chromosomes uncoil
- nuclear membrane reforms

12. Telophase
Chromosomes Uncoil
New Nuclear Membrane Forms

13. Phases of Mitosis

14. How do you remember the order of the phases of Mitosis?
Just remember this phrase……….

15. PMAT
PEE
MATT
P = Prophase
M = Metaphase
A = Anaphase
T = Telophase

16. Cytokinesis
- cell membrane forms a cleavage furrow and cytoplasm divides
- in plants, a cell plate forms between each cell

17. Cytokinesis
Cleavage Furrow