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Coagulation, fibrinolysis, and platelet activation in patients undergoing open and endovascular repair of abdominal aortic aneurysm  Robert S.M. Davies,

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Presentation on theme: "Coagulation, fibrinolysis, and platelet activation in patients undergoing open and endovascular repair of abdominal aortic aneurysm  Robert S.M. Davies,"— Presentation transcript:

1 Coagulation, fibrinolysis, and platelet activation in patients undergoing open and endovascular repair of abdominal aortic aneurysm  Robert S.M. Davies, MBChB, MMEd, MRCS, Mohamed Abdelhamid, MRCS, Michael L. Wall, MBChB, MRCS, Rajiv K. Vohra, PhD, FRCS, Andrew W. Bradbury, BSc, MBA, MD, FRCSEd, Donald J. Adam, MD, FRCSEd  Journal of Vascular Surgery  Volume 54, Issue 3, Pages (September 2011) DOI: /j.jvs Copyright © 2011 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Coagulation cascade. Biomarkers described in the review are highlighted in red. APC, Activated protein C; APC-PCI, activated protein C-protein C inhibitor complex; ATIII, antithrombin III; F1+2, prothrombin fragments 1 and 2; FM-F, fibrin monomer-fibrinogen complex; Plt, platelets; PS, proteins; SP-selectin, soluble P-selectin; TF, tissue factor; TM-IIa, thrombo-modulin-thrombin complex; TAT, thrombin-antithrombin complex; vWF, von Willebrand factor. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2011 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Diagrammatic representation of the fibrinolytic pathway. Biomarkers described in the review are highlighted in red. FDP, Fibrinogen degradation product; PAI-1, plasminogen activator inhibitor type-1; PIC, plasmin inhibitor complex; tPA, tissue plasminogen activator. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2011 Society for Vascular Surgery Terms and Conditions


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